SPIRIT 2025 statement: updated guideline for protocols of randomised trials [0.03%]
精神疾病随机对照试验SPIRIT 2025声明：报告试验过程的指南更新条款
An-Wen Chan,Isabelle Boutron,Sally Hopewell et al.
An-Wen Chan et al.
The protocol of a randomised trial is the foundation for study planning, conduct, reporting, and external review. However, trial protocols vary in their completeness and often do not address key elements of design and conduct. The SPIRIT (S...
Mezigdomide, carfilzomib, and dexamethasone versus carfilzomib and dexamethasone in patients with relapsed or refractory multiple myeloma (SUCCESSOR-2): a phase 3, open-label, randomised controlled trial [0.03%]
美吉Disposition、卡非佐米和地塞米松与卡非佐米和地塞米松治疗复发或难治性多发性骨髓瘤患者的疗效比较（SUCCESSOR-2）：一项三期、开放标签、随机对照试验
Meletios A Dimopoulos,Fredrik Schjesvold,Chengcheng Fu et al.
Meletios A Dimopoulos et al.
Background: A growing number of patients with multiple myeloma are anti-CD38 antibody-exposed and lenalidomide-exposed at first relapse, subsequently limiting their treatment options. Mezigdomide, a potent cereblon E3 lig...
Arri Coomarasamy,Adam J Devall,Sarah Bell et al.
Arri Coomarasamy et al.
Postpartum haemorrhage (PPH) is common, affecting an estimated 13% of women having vaginal birth and 31% of women having caesarean birth. Successful management of PPH requires early and accurate diagnosis and effective treatment. A systemat...
Postpartum haemorrhage: epidemiology, consequences, and missed opportunities [0.03%]
产后出血：流行病学、影响及诊治现状
Arri Coomarasamy,Kulandaipalayam N Sindhu,Ioannis Gallos et al.
Arri Coomarasamy et al.
Excessive bleeding after childbirth, known as postpartum haemorrhage (PPH), can turn an uncomplicated birth into a catastrophe. Each year, PPH occurs in an estimated 27 million women worldwide-17 million after vaginal birth and 10 million d...
Ruth Bonita,Robert Beaglehole
Ruth Bonita
Prevention of postpartum haemorrhage: from evidence to implementation at scale [0.03%]
产后出血的预防：从证据到大规模实施
Ioannis D Gallos,Kulandaipalayam N Sindhu,Idnan Yunas et al.
Ioannis D Gallos et al.
Postpartum haemorrhage (PPH) is a leading cause of maternal death. Preventing PPH can spare women from experiencing the trauma and risks of PPH, reduce the strain on overstretched health systems, and probably produce better outcomes than a ...
Udani Samarasekera
Udani Samarasekera
The impact of Chile's multipronged food labelling and advertising law on early childhood excess weight: a cohort difference-in-differences study [0.03%]
多管齐下的食品标签和广告法规对智利幼儿体重超标的影响：前后对照的队列差异分析研究
Guillermo Paraje,Nieves Valdés,Alberto Vega Macaya et al.
Guillermo Paraje et al.
Background: The 2016 Chilean Food Labelling and Advertising Law (FLAL), featuring black octagonal front-of-package warning labels and marketing and school restrictions, was among the first sets of multiple healthy food po...
Simone Pettigrew,Daisy Coyle
Simone Pettigrew