Roberta Caruso,Bernard C Lo,Gabriel Núñez
Roberta Caruso
The mammalian intestine is colonized by trillions of microorganisms that have co-evolved with the host in a symbiotic relationship. The presence of large numbers of symbionts near the epithelial surface of the intestine poses an enormous ch...
Darrell J Irvine,Eric L Dane
Darrell J Irvine
Therapeutic targeting of the immune system in cancer is now a clinical reality and marked successes have been achieved, most notably through the use of checkpoint blockade antibodies and chimeric antigen receptor T cell therapy. However, ef...
Jennifer L Gommerman
Jennifer L Gommerman
B cells, plasma cells and antibody repertoires in the tumour microenvironment [0.03%]
肿瘤微环境中B细胞、浆细胞和抗体库 repertoire
George V Sharonov,Ekaterina O Serebrovskaya,Diana V Yuzhakova et al.
George V Sharonov et al.
Recent data show that B cells and plasma cells located in tumours or in tumour-draining lymph nodes can have important roles in shaping antitumour immune responses. In tumour-associated tertiary lymphoid structures, T cells and B cells inte...
Yvonne Bordon
Yvonne Bordon
Kirsty Minton
Kirsty Minton
Dhouha Daassi,Kathleen M Mahoney,Gordon J Freeman
Dhouha Daassi
The interaction of programmed cell death 1 ligand 1 (PDL1) with its receptor programmed cell death 1 (PD1) inhibits T cell responses, and blockade of this interaction has proven to be an effective immunotherapy for several different cancers...
Rémy Bosselut
Rémy Bosselut
Myeloid PD1 in the frame [0.03%]
髓系PD1受关注
Lucy Bird
Lucy Bird
Padmanee Sharma,James P Allison
Padmanee Sharma