Jeremy G Baldwin,Christoph Heuser-Loy,Luca Gattinoni
Jeremy G Baldwin
Organelles are the internal batteries, gears, actuators, 3D printers and transmitters that drive cell function. Their composition and activity vary between cell types depending on functional demands. In T cells, which are key mediators of i...
Yvonne Bordon
Yvonne Bordon
Alexandra Flemming
Alexandra Flemming
Alexandra Flemming
Alexandra Flemming
Enterobacteriaceae-derived cadaverine manipulates gut macrophage metabolism [0.03%]
肠杆菌科来源的尸胺可调节肠道巨噬细胞代谢
Alexandra Flemming
Alexandra Flemming
Jasia Mahdi,Vrunda Trivedi,Michelle Monje
Jasia Mahdi
The nervous and immune systems are intricately linked to one another through bi-directional crosstalk. Given the limited therapeutic options for aggressive and refractory central nervous system (CNS) tumours, immunotherapies are increasingl...
Kirsty Minton
Kirsty Minton
Qinli Sun,Chen Dong
Qinli Sun
T cell exhaustion is an adaptive and distinct cell fate that emerges in response to persistent antigen stimulation, primarily in chronic infections and cancer. It is characterized by a progressive loss of effector functions and sustained ex...
Rayne H Rouce
Rayne H Rouce
Lessons from neoadjuvant immunotherapy in melanoma: understanding antitumour immunity and tumour escape [0.03%]
免疫治疗应用于黑色素瘤的新辅助治疗的启示：理解抗肿瘤免疫和肿瘤逃逸机制
Francesca Fallarino,Christian U Blank
Francesca Fallarino
Immunotherapy has become a fourth pillar of cancer therapy, alongside surgery, radiotherapy and chemotherapy. Cancer immunotherapy seems to be most effective in the context of low but not negligible tumour burden, thus in the neoadjuvant se...