Sirpa Jalkanen,Marko Salmi
Sirpa Jalkanen
The influx and efflux of cells and antigens to and from the draining lymph nodes largely take place through the subcapsular, cortical and medullary sinus systems. Recent analyses in mice and humans have revealed unexpected diversity in the ...
Kirsty Minton
Kirsty Minton
David R Collins,Gaurav D Gaiha,Bruce D Walker
David R Collins
HIV infection can be effectively treated by lifelong administration of combination antiretroviral therapy, but an effective vaccine will likely be required to end the HIV epidemic. Although the majority of current vaccine strategies focus o...
Yvonne Bordon
Yvonne Bordon
Kirsty Minton
Kirsty Minton
Lucy Bird
Lucy Bird
Immune crosstalk in cancer progression and metastatic spread: a complex conversation [0.03%]
肿瘤进展和转移过程中免疫交叉对话：一种复杂的交流方式
Hannah Garner,Karin E de Visser
Hannah Garner
Metastatic disease is responsible for approximately 90% of cancer deaths. For successful dissemination and metastasis, cancer cells must evade detection and destruction by the immune system. This process is enabled by factors secreted by th...
Rethinking mucosal antibody responses: IgM, IgG and IgD join IgA [0.03%]
重新思考黏膜抗体反应：IgM、IgG和IgD与IgA齐头并进
Kang Chen,Giuliana Magri,Emilie K Grasset et al.
Kang Chen et al.
Humoral immune responses at mucosal surfaces have historically focused on IgA. Growing evidence highlights the complexity of IgA-inducing pathways and the functional impact of IgA on mucosal commensal bacteria. In the gut, IgA contributes t...
Jose Ordovas-Montanes,Semir Beyaz,Seth Rakoff-Nahoum et al.
Jose Ordovas-Montanes et al.
Memories of previous immune events enable barrier tissues to rapidly recall distinct environmental exposures. To effectively inform future responses, these past experiences can be stored in cell types that are long-term residents or essenti...
Shocking HIV out of hiding [0.03%]
唤醒隐藏的艾滋病病毒
Alexandra Flemming
Alexandra Flemming