Dorothée L Berthold,Catherine Wormald
Dorothée L Berthold
Clarissa Coveney,Jennifer Alderson
Clarissa Coveney
Thymic development of unconventional T cells: how NKT cells, MAIT cells and γδ T cells emerge [0.03%]
胸腺中非常见T细胞的发育：NKT细胞、MAIT细胞和γδT细胞的产生机制
Daniel G Pellicci,Hui-Fern Koay,Stuart P Berzins
Daniel G Pellicci
T cell lineages are defined by specialized functions and differential expression of surface antigens, cytokines and transcription factors. Conventional CD4+ and CD8+ T cells are the best studied of the T cell subsets, but 'unconventional' T...
GM-CSF-based treatments in COVID-19: reconciling opposing therapeutic approaches [0.03%]
COVID-19中GM-CSF的治疗作用：调和对立的治疗理念
Frederick M Lang,Kevin M-C Lee,John R Teijaro et al.
Frederick M Lang et al.
Therapeutics against coronavirus disease 2019 (COVID-19) are urgently needed. Granulocyte-macrophage colony-stimulating factor (GM-CSF), a myelopoietic growth factor and pro-inflammatory cytokine, plays a critical role in alveolar macrophag...
Matthew D Park
Matthew D Park
Nicolas Vabret
Nicolas Vabret
Alexandra Tabachnikova,Steven T Chen
Alexandra Tabachnikova
Lucy Bird
Lucy Bird
Severe COVID-19 in the young and healthy: monogenic inborn errors of immunity? [0.03%]
年轻的健康人群中的重症新冠肺炎：单基因先天性免疫缺陷病？
Shen-Ying Zhang,Qian Zhang,Jean-Laurent Casanova et al.
Shen-Ying Zhang et al.
Severe COVID-19 is rare in previously healthy individuals who are less than 50 years of age, affecting probably no more than 1 in 1,000 such infected individuals. We suggest that these patients may become critically ill because of monogenic...
Rebecca E Chandler
Rebecca E Chandler
Evolution of the current infrastructure for surveillance of vaccine safety will be essential to meet our commitments to the public in the deployment of a vaccine (or vaccines) to COVID-19. The incorporation of concepts and tools within the ...