Bérengère Salomé,Zafar Mahmood
Bérengère Salomé
Matthew D Park
Matthew D Park
BCG-induced trained immunity: can it offer protection against COVID-19? [0.03%]
卡介苗诱导的训练免疫是否可以对抗COVID-19？
Luke A J O&#x;Neill,Mihai G Netea
Luke A J O&#x;Neill
Bacillus Calmette–Guérin (BCG) vaccination has been reported to decrease susceptibility to respiratory tract infections, an effect proposed to be mediated by the general long-term boosting of innate immune mechanisms, also termed trained ...
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages [0.03%]
新型冠状病毒感染患者的病理炎症：单核细胞和巨噬细胞起关键作用
Miriam Merad,Jerome C Martin
Miriam Merad
The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than 200,000 deaths worldwide. Several studies have now established that the hyperinflammatory response induced by SARS-CoV-2 is a major cause of disease severity and...
Lucy Bird
Lucy Bird
Heterogeneity in the initiation, development and function of type 2 immunity [0.03%]
2型免疫的启动、发展和功能的异质性
William C Gause,Carla Rothlin,P&#x;ng Loke
William C Gause
Type 2 immune responses operate under varying conditions in distinct tissue environments and are crucial for protection against helminth infections and for the maintenance of tissue homeostasis. Here we explore how different layers of heter...
Omar Pacha,Mary Alice Sallman,Scott E Evans
Omar Pacha
IL-17 and IL-17 receptor inhibitors boast an impressive safety history and are widely available. Here, we argue that targeting IL-17 is immunologically plausible as a strategy to prevent acute respiratory distress syndrome (ARDS) in coronav...
Will helminth co-infection modulate COVID-19 severity in endemic regions? [0.03%]
寄生虫共感染会调节新冠疫情地区的疫情严重程度吗？
Richard S Bradbury,David Piedrafita,Andrew Greenhill et al.
Richard S Bradbury et al.
As COVID-19 spreads through the world, most cases to date are in middle- and high-income nations. The impact on resource-poor nations remains unknown. Amongst many factors likely to affect the impact of COVID-19 in these areas, co-infection...
Allan M Mowat
Allan M Mowat
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Published Erratum
Nature reviews. Immunology. 2020 Jul;20(7):448. DOI:10.1038/s41577-020-0329-y 2020
Emma Risson
Emma Risson