CDKN2Alow tumours mediate immunotherapy resistance by depriving macrophages of zinc [0.03%]
低CDKN2A肿瘤通过剥夺巨噬细胞锌元素来介导免疫治疗耐药性
Robbie Jin,Tracy L McGaha
Robbie Jin
Felix Clemens Richter,Kelsey Voss
Felix Clemens Richter
Kirsty Minton
Kirsty Minton
Victoria Male,Christine E Jones
Victoria Male
Infectious diseases pose a particular risk to newborns and there is a global need to protect this vulnerable group. Because of the challenges of developing vaccines that are effective in newborns, only the hepatitis B and tuberculosis vacci...
Patterns of pathogenesis in innate immunity: insights from C. elegans [0.03%]
获得性免疫中的致病机理模式——来自秀丽隐杆线虫的启示
Samantha Tse-Kang,Khursheed A Wani,Read Pukkila-Worley
Samantha Tse-Kang
The cells in barrier tissues can distinguish pathogenic from commensal bacteria and target inflammatory responses only in the context of infection. As such, these cells must be able to identify pathogen infection specifically and not just t...
Atsushi Kato,Hirohito Kita
Atsushi Kato
Asthma and chronic rhinosinusitis (CRS) are common chronic inflammatory diseases of the respiratory tract that have increased in prevalence over the past five decades. The clinical relationship between asthma and CRS has been well recognize...
The diversity of CD8+ T cell dysfunction in cancer and viral infection [0.03%]
癌症和病毒感染中CD8+t细胞功能障碍的多样性
Lorenzo Galluzzi,Kellie N Smith,Adrian Liston et al.
Lorenzo Galluzzi et al.
CD8+ T cells that are repeatedly exposed to antigenic stimulation, such as in the context of progressing neoplasms and chronic viral infections, acquire a dysfunctional or hypofunctional state that is generally known as exhaustion. There ha...
How to respond when biomedical science and global health is under existential threat [0.03%]
面对生物医学科学和全球卫生面临生存威胁时的应对策略
Daniel M Altmann,Angela L Rasmussen
Daniel M Altmann
Yvonne Bordon
Yvonne Bordon