Mohottige D Neranjan Tharuka,Asimina S Courelli,Yuan Chen
Mohottige D Neranjan Tharuka
Post-translational protein modifications by the small ubiquitin-like modifier (SUMO) family have been shown to regulate immune cells in the context of infection, autoimmunity and, more recently, cancer. Recent clinical trials investigating ...
Yvonne Bordon
Yvonne Bordon
Neutrophils are dispensable for Shigella control: macrophages take centre stage [0.03%]
中性粒细胞对志贺菌的控制并非必需：巨噬细胞占主导地位
Didem Ağaç Çobanoğlu,James P Allison
Didem Ağaç Çobanoğlu
Mapping the developmental trajectory and recruitment of memory-phenotype Ly49+CD8+ T cells [0.03%]
记忆表型Ly49+CD8+ T细胞的发育轨迹和募集映射
Guillaume J Trusz,Verena van der Heide
Guillaume J Trusz
Defining immune reset: achieving sustained remission in autoimmune diseases [0.03%]
定义免疫重置：实现自身免疫性疾病的持续缓解
Tobias Junt,Thomas Calzascia,Elisabetta Traggiai et al.
Tobias Junt et al.
Personalized cell therapies for autoimmune diseases - such as autologous haematopoietic stem cell transplantation and chimeric antigen receptor-expressing T cells - have the potential to achieve sustained remission in patients with certain ...
New insights into the noncanonical inflammasome point to caspase-4 as a druggable target [0.03%]
对非典型炎症小体的新认识将半胱天冬酶-4指认为可药物作用的目标蛋白
Elad Elkayam,Francois G Gervais,Hao Wu et al.
Elad Elkayam et al.
Recent studies indicate that the human lipopolysaccharide sensor caspase-4, unlike its mouse homologue caspase-11, is constitutively expressed and activates pro-IL-18 as well as gasdermin D-mediated pyroptosis. Activation of human caspase-4...
PerturbView: scalable image-based perturbation screens in cells and tissues [0.03%]
扰动视图：细胞和组织中可扩展的图像扰动筛选
Takamasa Kudo
Takamasa Kudo
Lorenzo Galluzzi
Lorenzo Galluzzi
DOTS: DNA origami tension sensors for studying T cell mechanobiology [0.03%]
DOTS：用于研究T细胞机生物力学的DNA折纸张力传感器
Sarah Al Abdullatif
Sarah Al Abdullatif
Type 1 immune response reduces seizure risk after traumatic brain injury [0.03%]
创伤性脑损伤后I型免疫反应可降低癫痫发作风险
Jennifer S Y Ahn,Jennifer L Gommerman
Jennifer S Y Ahn