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期刊名:Nature reviews immunology

缩写:NAT REV IMMUNOL

ISSN:1474-1733

e-ISSN:1474-1741

IF/分区:60.9/Q1

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Macrophages are active participants of tissue repair and when normal repair processes fail, fibrosis can ensue, which leads to major organ dysfunction and affects nearly a billion people worldwide. Here we focus on macrophages in the spatio...
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Many inhibitory receptors that regulate immune cell function recognize a limited number of specific ligands. However, a subgroup of so-called inhibitory pattern recognition receptors (iPRRs) can bind a much larger array of ligands of struct...
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The central nervous system (CNS) has a unique relationship with the immune system, referred to as immune privilege. For many years it was thought that immune privilege was due to isolation of the CNS from the immune system, but recent findi...
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Cytotoxic lymphocytes counter intracellular pathogens and cancer by recognizing and destroying infected or transformed target cells. The basis for their function is the cytolytic immune synapse, a structurally stereotyped cell-cell interfac...