Comparison of the protective effects of silymarin and thymoquinone in the focal cerebral ischemia-reperfusion rat model [0.03%]
茋类和鼠尾草脑素通过PI3K/Akt信号通路对局灶性脑缺血再灌注损伤大鼠的神经保护作用的比较研究
Merve Solmaz,Ender Erdogan,Dervis Dasdelen et al.
Merve Solmaz et al.
Silymarin and thymoquinone exert neuroprotective effects, although their combined effects in focal cerebral ischemia/reperfusion (I/R) models are unknown. We compared the effect of silymarin and thymoquinone in an I/R rat model. Wistar rats...
The number and distribution of proliferating cells in the rat's rostral migratory stream as identified by means of two different proliferation markers [0.03%]
两种增殖标记物鉴定的大鼠纹状体迁移流中的增殖细胞的数量和分布
Kamila Fabianová,Adam Raček,Alexandra Popovičová et al.
Kamila Fabianová et al.
In the brains of adult rodents, the cells arising in the subventricular zone of the lateral ventricles maintain the ability to divide when migrating to the olfactory bulb along the rostral migratory stream (RMS). Dividing cells in the RMS a...
Therapeutic effect of berberine against 5-fluorouracil induced ovarian toxicity in rats [0.03%]
治疗小鼠5-氟尿嘧啶诱导的卵巢毒性的药物研究表明巴马汀具有保护作用
Selim Demir,Nihal Turkmen Alemdar,Hatice Kucuk et al.
Selim Demir et al.
Berberine (BER) is a naturally occurring alkaloid with a multitude of beneficial effects on human health. Although it is one of the most studied phytochemicals, its curative effect against ovarian damage caused by 5-fluorouracil (5-FU) has ...
Effects of licorice root (Glycyrrhiza glabra) extract on the livers of obese rats [0.03%]
甘草(Glycyrrhiza glabra)提取物对肥胖大鼠肝脏的影响
Ahmet Uyar,Barış Özdere,Turan Yaman et al.
Ahmet Uyar et al.
We have investigated anti-obesity effects of the extract of licorice (Glycyrrhiza glabra) root in rats with diet-induced obesity and hyperlipidemia by using histopathological and biochemical methods. Thirty-two Wistar albino rats were divid...
The effect of bisphenol A on the Notch (Notch2 and Jagged2) signaling pathway in the follicular development of the neonatal rat ovary [0.03%]
双酚A对新生鼠卵巢窦前卵泡发育中Notch（Notch2和Jagged2）信号通路的影响研究
Özlem Özden Akkaya,Artay Yağci,Berrin Zik et al.
Özlem Özden Akkaya et al.
The formation of primordial follicles determines the pool size of follicles in the ovary, and is crucial for female reproductivity. Oocyte nest breakdown, and the formation of primordial follicles, largely depend upon the communication betw...
Optimized biomarker evaluation and molecular testing in the era of breast cancer precision medicine [0.03%]
精准医学时代乳腺癌生物标志物评估和分子检测的优化
David G Hicks,Bradley M Turner
David G Hicks
Ground breaking advances in medicine, driven in part by major technologic developments in molecular biology have led us to a new model for cancer care that has been termed personalized, or precision medicine. Precision medicine is a model f...
Histopathologic effects of obstetric gel on the vaginal tissue: in vaginal trauma formed rat model [0.03%]
一种产科润滑凝胶对阴道组织的病理影响：在因阴道创伤形成的大鼠模型中的作用
Selçuk Kaplan,Bilge Aydın Türk,Ebru Elibol et al.
Selçuk Kaplan et al.
The present study aimed to investigate the histopathological effects of obstetric gel (OG) on vaginal tissue. In this study, 21 female Wistar albino rats were divided into three groups, comprising seven animals in each group. The first grou...
Leica Barnhart,Chloe Balzer,Sheila Criswell
Leica Barnhart
Helicobacter pylori, a curved bacterial rod and causative agent of peptic ulcer and gastric adenocarcinoma, is found as an infectious agent in the stomach of over half of the global population. H. pylori has been identified in oral biofilms...
Hesperetin regulates PI3K/Akt and mTOR pathways to exhibit its antiproliferative effect against colon cancer cells [0.03%]
柚皮素通过调节PI3K/Akt和mTOR信号途径抑制结肠癌细胞增殖作用
Gowrikumar Saiprasad,Palanivel Chitra,Ramar Manikandan et al.
Gowrikumar Saiprasad et al.
Hesperetin, a citrus flavonoid, has been a widely studied anticancer agent against many types of cancers, but the exact mechanism of efficacy is still unrevealed. Therefore, this study has attempted to delineate the mechanical aspect of hes...
Effect of abemaciclib and curcumin administration on sex hormones, reproductive functions, and oxidative DNA expression in rats [0.03%]
阿贝西利和姜黄素对大鼠性激素、生殖功能及氧化应激DNA表达的影响
Zübeyir Huyut,Bünyamin Uçar,Kenan Yıldızhan et al.
Zübeyir Huyut et al.
This study investigated whether abemaciclib (ABE) administration had any adverse effects on ovarian and sex hormones in female rats, and the protective effect of curcumin. Forty female rats were equally divided into the sham control, DMSO, ...