Silymarin protects against doxorubicin induced cardiotoxicity by down-regulating topoisomerase IIβ expression in mice [0.03%]
奶蓟素通过下调拓扑异构酶IIβ表达保护小鼠心脏免受多柔比星的心脏毒性损伤
Emrah İpek,Recai Tunca
Emrah İpek
We investigated the potential protective effects of silymarin (SLY) on doxorubicin (DOX) induced chronic cardiotoxicity in mice. We used 30 male BALB/c mice assigned randomly to four experimental groups: control group administered normal sa...
Modeling the extent of conjugation in histochemical dyes and fluorescent probes: clarification in calculating conjugated bond number (CBN) and introduction of a new parameter, resonance energy [0.03%]
染料和荧光探针偶联程度的建模：计算偶联键数目(CBN)的澄清及一个新的参数共振能量的引入
Richard W Dapson,Richard W Horobin
Richard W Dapson
Determining the extent of conjugation in dyes and fluorochromes is a helpful tool for understanding or predicting the behavior of these compounds when used as stains for microscopy. One measure that has been used repeatedly is conjugated bo...
Evaluation of DNA damage in obese children using the chromatin dispersion test [0.03%]
采用染色质分散试验评估肥胖儿童DNA损伤情况
Martha I Dávila-Rodríguez,Francisco González-Salazar,Manuel López-Cabanillas et al.
Martha I Dávila-Rodríguez et al.
Childhood obesity predicts adult obesity and may increase the lifetime risk of adverse health outcomes. Obesity is characterized by oxidative stress that can induce DNA damage; however, studies of childhood and adolescent obesity are scarce...
Role of p38 MAPK, Akt and NFκB in renoprotective effects of nebivolol on renal ischemia-reperfusion injury in rats [0.03%]
Nebivolol通过活化p38MAPK、Akt和NFκB信号通路发挥对大鼠肾缺血再灌注损伤的肾脏保护作用及其机制研究
Zahide Cavdar,Ayse Kocak,Cemre Ural et al.
Zahide Cavdar et al.
Renal ischemia-reperfusion (I-R) injury is a complex pathophysiologic condition characterized by oxidative stress, inflammation and apoptosis. We investigated the potential renoprotective effect of nebivolol, a β1 adrenergic receptor block...
Seed coating with micronutrients improves germination, growth, yield and microelement nutrients of maize (Zea mays L.) [0.03%]
微量元素包衣改善玉米的萌发、生长、产量和微量营养素含量
Fa-Bo Chen,Yun-Chao Feng,Shi-Ping Huo
Fa-Bo Chen
Soil and foliar application are the most widely used methods for adding micronutrients to maize. High quality micronutrient fertilizers, however, are difficult to obtain in developing countries; micronutrient seed coatings are an attractive...
Inula viscosa ameliorates acetic acid induced ulcerative colitis in rats [0.03%]
Inula viscosa改善醋酸诱导的Sprague-Dawley大鼠溃疡性结肠炎
Mustafa Cellat,İbrahim Ozan Tekeli,Erdinç Türk et al.
Mustafa Cellat et al.
Increased pro-inflammatory cytokines and oxidative stress contribute to the pathophysiology of ulcerative colitis (UC). Inula viscosa is a plant with antioxidant and anti-inflammatory properties. We investigated the effect of an ethanolic e...
Transmission electron microscopy assessment of a novel method for isolating pure exosomes from serum [0.03%]
透射电镜评估新型分离血清纯外泌体方法
Jin Wen,Zhijun Zhang,Gang Feng et al.
Jin Wen et al.
Serum exosomes frequently are used for liquid biopsy. Serum exosomes normally are isolated using ultracentrifugation; however, ultracentrifugation is time-consuming, labor intensive and requires a high-speed centrifuge. Many commercial kits...
Effect of melatonin on low and high dose radiotherapy induced thyroid injury [0.03%]
褪黑素对不同剂量放射性损伤甲状腺的保护作用及机制研究
Serhat Aras,I Hsan Oğuz Tanzer,Seyhan Karaçavuş et al.
Serhat Aras et al.
We investigated the radioprotective effect of melatonin (MEL) against thyroid gland damage in rats caused by flattening filter (FF) and flattening filter free (FFF) single dose X-ray beams. We used 48 female rats divided into six groups of ...
Maternal dietary zinc status alters offspring female mammary gland development and response to acute 7,12-dimethylbenzanthracene insult [0.03%]
母体膳食锌状况改变子代雌性乳腺发育及急性7,12-二甲基苯并蒽刺激的响应
Flávia R M da Silva,Joyce R Zapaterini,Tony F Grassi et al.
Flávia R M da Silva et al.
We evaluated the effects of prenatal and postnatal dietary zinc (Zn) deficiency or supplementation on mammary gland morphology and on acute response to 7,12-dimethylbenzanthracene (DMBA) in pubertal female rats. On gestational day 10 (GD 10...
RAS gene mutations and histomorphometric measurements in oral squamous cell carcinoma [0.03%]
口腔鳞状细胞癌中的RAS基因突变与组织形态测量研究
Tazeen Mustansar,Talat Mirza,Mushtaq Hussain
Tazeen Mustansar
Members of the RAS gene family frequently are mutated in cancers including oral squamous cell carcinoma (OSCC). We investigated the correlation of histological characteristics of OSCC with RAS gene mutations. We graded tumors and extracted ...