Jenny van der Wijst,René J M Bindels,Joost G J Hoenderop
Jenny van der Wijst
Purpose of review: The tight control of blood magnesium (Mg) levels is of central importance for numerous physiological processes. A persistent low Mg status (hypomagnesemia) is associated with severe health risks and is ...
Alan C Pao
Alan C Pao
Purpose of review: Dr Arthur Guyton hypothesized that the capacity of the kidney to excrete sodium ultimately dictates long-term changes in blood pressure. This model has had a profound influence on our understanding of b...
Ming Chang Hu,Makoto Kuro-o,Orson W Moe
Ming Chang Hu
Purpose of review: Cardiovascular disease remains the single most serious contributor to mortality in chronic kidney disease (CKD). Although conventional risk factors are prevalent in CKD, both cardiomyopathy and vasculop...
Coupling fibroblast growth factor 23 production and cleavage: iron deficiency, rickets, and kidney disease [0.03%]
耦合成纤维细胞生长因子23的生成和裂解：缺铁、佝偻病与肾病之间的关联
Myles Wolf,Kenneth E White
Myles Wolf
Purpose of review: High levels of fibroblast growth factor 23 (FGF23) cause the rare disorders of hypophosphatemic rickets and are a risk factor for cardiovascular disease and death in patients with chronic kidney disease...
Laura A New,Claire E Martin,Nina Jones
Laura A New
Purpose of review: The podocyte slit diaphragm is a fundamental component of the glomerular filtration barrier and its function is highly dependent on the maintenance of specialized actin-based projections known as foot p...
Hakan R Toka
Hakan R Toka
Purpose of review: Variations in extracellular calcium level have a large impact on kidney function. Most of the effects seen are attributed to the calcium-sensing receptor (CaSR), a widely expressed G-protein-coupled cel...
Can one evaluate bone disease in chronic kidney disease without a biopsy? [0.03%]
无需活检能否评估慢性肾脏病患者的骨病？
Revekka Babayev,Thomas L Nickolas
Revekka Babayev
Purpose of review: Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a complex disorder of bone and mineral metabolism that results in an excess risk of fractures, cardiovascular events and mortality. The mana...
Marta Christov
Marta Christov
Purpose of review: To review the emerging literature on changes in fibroblast growth factor 23 (FGF23) levels in the setting of acute kidney injury (AKI). ...
Joseph S Uzarski,Yun Xia,Juan C I Belmonte et al.
Joseph S Uzarski et al.
Purpose of review: The severe shortage of suitable donor kidneys limits organ transplantation to a small fraction of patients suffering from end-stage renal failure. Engineering autologous kidney grafts on-demand would po...
Xiaojing Tang,John C Lieske
Xiaojing Tang
Purpose of review: Nephrolithiasis is a common systemic disease associated with both acute kidney injury (AKI) and chronic kidney disease (CKD). The purpose of this review is to discuss recent publications regarding nephr...