The plumbing problem: rising antimicrobial resistance in building water systems [0.03%]
管道问题:建筑给水系统中抗菌素耐药性加剧
Claire Hayward,Harriet Whiley,Nicholas J Ashbolt
Claire Hayward
Purpose of review: This review examines the interplay between biological and anthropogenic factors in the development and persistence of antimicrobial resistance (AMR) within building plumbing systems, which is of particu...
Respiratory syncytial virus prevention in immunocompromised hosts: gaps and opportunities [0.03%]
免疫功能低下宿主呼吸道合胞病毒的预防:差距和机遇
Alastair Murray,Helen Y Chu
Alastair Murray
Purpose of review: Respiratory syncytial virus (RSV) poses a significant threat to immunocompromised individuals, yet preventive strategies and treatments remain largely unstudied in this population. New vaccines, mAbs, a...
Latent tuberculosis screening and treatment in solid organ and hematopoietic stem cell transplant candidates and recipients [0.03%]
器官移植和造血干细胞移植受者和供者的潜伏结核感染筛查与治疗
Sonya Krishnan,Robin Avery,Veronica Dioverti et al.
Sonya Krishnan et al.
Purpose of review: Tuberculosis disease (TBD) has high mortality in transplant recipients. This review evaluates the current evidence for latent tuberculosis infection (LTBI) screening and treatment in solid organ transpl...
Genome-wide approaches to bacterial strain typing: a history and review of recent methodological advances [0.03%]
细菌菌株分型的基因组方法:历史回顾及近期研究进展综述
William C Shropshire,Blake M Hanson,Samuel A Shelburne
William C Shropshire
Purpose of review: Whole genome sequencing (WGS) has transformed bacterial strain typing, an essential tool for outbreak detection, antimicrobial resistance surveillance, and tracking clonal emergence across clinical, res...
Donald C Vinh
Donald C Vinh
Purpose of review: The limitations of pathogen-directed therapies include growing antimicrobial resistance or the complete lack of any effective antimicrobial agents. This review highlights the potential for host-directed...
The role of antibacterial prophylaxis in high-risk neutropenia: benefits, risks, and current perspectives [0.03%]
抗菌预防在高危中性粒细胞减少症中的作用:益处、风险及当前观点
Abby P Douglas,Erica Stohs,Malgorzata Mikulska
Abby P Douglas
Purpose of review: To review the benefits, risks and specific considerations surrounding antibacterial prophylaxis (ABP) in adults with neutropenia, focusing primarily on high-risk patients with hematologic malignancies (...
Marie-Céline Zanella,Chanu Rhee,Michael Klompas
Marie-Céline Zanella
Purpose of review: The COVID-19 pandemic catalyzed new insights into respiratory viral transmission mechanisms and prevention. We review the most practical and impactful measures to prevent SARS-CoV-2 and other nosocomial...
Lenacapavir: a first-in-class capsid inhibitor for HIV treatment and prevention [0.03%]
.Lenacapavir:一种用于治疗和预防HIV的新一类衣壳抑制剂
Mehri S McKellar
Mehri S McKellar
Purpose of review: This review summarizes available data for lenacapavir (LEN), a first-in-class agent that targets several functions of the HIV capsid in the viral cycle, including nuclear entry, viral assembly, and caps...