"O for KP": an evidence review on recentering HIV prevention and PrEP delivery for key populations and the underserved [0.03%]
“O for KP”：针对重点人群和弱势群体重新定位艾滋病毒预防和暴露前预防药物递送的证据回顾
Warittha Tieosapjaroen,Cheryl C Johnson,Jason J Ong
Warittha Tieosapjaroen
Purpose of review: Despite the proven efficacy of preexposure prophylaxis (PrEP), global coverage remains far below targets, with the greatest gaps among key and underserved populations. This review is timely as it highli...
Michelle Collins-Ogle,Betsy C Herold
Michelle Collins-Ogle
Purpose of review: Genital herpes is a major worldwide public health problem with more than four billion people infected with either herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2). To reduce HSV infections, which g...
Haemophilus ducreyi in genital ulcer disease: new developments in an old disease [0.03%]
杜克雷嗜血杆菌与生殖器溃疡病：旧疾新进展
Philippe Ndzomo,Sara Eyangoh
Philippe Ndzomo
Purpose of review: Haemophilus ducreyi remains an important, though often overlooked, cause of genital ulcer disease (GUD), particularly in contexts where syndromic management limits pathogen-specific diagnosis. Although ...
Antiviral clinical trial design throughout the COVID pandemic: evolving endpoints and lessons learnt [0.03%]
新冠肺炎疫情期间的抗病毒临床试验设计：不断变化的研究终点和经验教训
Beatrice Z Sim,Andre C Kalil,Cameron R Wolfe
Beatrice Z Sim
Purpose of review: Trial design during the novel coronavirus-19 (COVID-19) pandemic was stymied by significant uncertainty about the natural history of the virus, at-risk populations, and optimal patient care by investiga...
HIV and menopause: current evidence, gaps, and future directions for integrated care [0.03%]
HIV与更年期：现有证据、缺口及综合护理的未来方向
Unoda A Chakalisa,Susan Cole-Haley,Chelsea Morroni et al.
Unoda A Chakalisa et al.
Purpose of review: To synthesize current evidence on menopause in women living with HIV, highlighting the biological, psychosocial, and structural determinants of health, and to identify research and implementation gaps t...
Asimina Valsamaki,Konstantinos Mantzarlis,George Dimopoulos
Asimina Valsamaki
Purpose of review: Skin and soft tissue infections (SSTIs) are one of the most frequent infections that need management either in outpatient setting or as inpatient. The present review of the literature will present recen...
Claire Dendle
Claire Dendle
Purpose of review: Polyoma virus-associated haemorrhagic cystitis (PVA-HC) is a painful and high-morbidity complication after allogeneic hematopoietic stem cell transplantation (allo-HCT). It is characterized by haematuri...
Is it possible to identify genotypes underlying resistant phenotypes in Gram-negative pathogens? [0.03%]
能否在革兰氏阴性病原菌中鉴定出耐药表型的基因型？
Almudena Burillo,Julia Serrano-Lobo,Emilio Bouza et al.
Almudena Burillo et al.
Purpose of review: This review explores the relationship between genotypes and resistant phenotypes in Gram-negative pathogens. We analyse to what extent conventional phenotypic methods predict genetic mechanisms of resis...
Understanding antiviral intolerance in the management of cytomegalovirus; a scoping review [0.03%]
抗病毒耐受性在巨细胞病毒感染管理中的作用：系统评价
Violet Z Zhu,Priya Garg,Nikhil Singh et al.
Violet Z Zhu et al.
Purpose of review: Older antiviral agents for managing cytomegalovirus (CMV) infections post transplantation are associated with treatment limiting toxicities. Presently, there is no consensus on the definition of 'antivi...
Maddalena Peghin,Jay A Fishman,Paolo Antonio Grossi
Maddalena Peghin
Purpose of review: Pneumocystis jiroveci pneumonia (PJP) poses an important risk in immunodeficient patients. Several aspects of the pathogenesis and management of PJP remain poorly understood. The aim of this review is t...