Donor-derived latent viral and parasitic infections in solid organ transplant recipients: old foes and emerging challenges [0.03%]
器官移植受者中的供体衍生潜在病毒和寄生虫感染：老问题与新挑战
Robert C Wright,Sara Belga
Robert C Wright
Purpose of review: Anticipated donor-derived infections following solid organ transplantation are a unique type of iatrogenic infection where a transplant recipient is knowingly infected with a potential pathogen, where t...
Andreu Vilaseca,Michel Toledano,Eoin P Flanagan
Andreu Vilaseca
Purpose of review: To review recent advances in infectious myelopathies and integrate them into a practical, syndrome-based approach that supports early recognition, guides testing, and avoids pitfalls. ...
Genetic mechanisms underlying host susceptibility to central nervous system viral infections [0.03%]
中枢神经系统病毒感染宿主易感性的遗传机制
Rohit Benjamin,Darshan Pandya,Avindra Nath
Rohit Benjamin
Purpose of review: To provide a critical review of the literature on the influence of host genetic variations on the susceptibility to viral encephalitis, and the proposed underlying key immunogenetic mechanisms. ...
Ischaemia in tuberculous meningitis: update on pathophysiology, clinical predictors and management [0.03%]
结核性脑膜炎的缺血：病理生理、临床预测因素和处理策略的最新研究进展
Georgia Lamb,Reinout van Crevel,Graeme Meintjes et al.
Georgia Lamb et al.
Purpose of review: Tuberculous meningitis (TBM) is a severe manifestation of Mycobacterium tuberculosis infection, associated with high mortality and long-term neurological disability. Cerebral ischaemia and infarction ar...
Luisa F Alviz,Rodrigo Hasbun,Kiran T Thakur
Luisa F Alviz
Purpose of review: Bacterial meningitis remains a leading cause of preventable mortality and long-term neurological disability worldwide, despite the availability of effective diagnostics, antimicrobials, and vaccines. Hi...
Irene Mora Castaño,Rodrigo Hasbun
Irene Mora Castaño
Purpose of review: This review summarizes current evidence on the general epidemiology, routes of central nervous system (CNS) invasion, clinical manifestations, diagnostic approaches, and treatment considerations associa...
Karen N McCarthy,Kingston H G Mills
Karen N McCarthy
Purpose of review: We review the latest evidence that respiratory tissue resident memory T (TRM) cells are key to local and immediate adaptive immunity to bacterial and viral infections of the respiratory tract and the im...
Roba El Zibaoui,Arun Venkatesan
Roba El Zibaoui
Purpose of review: Infectious encephalitis (IE) is a serious neurological condition that poses a major global health threat. This review summarizes emerging pathogens, particularly arboviruses, updated diagnostic strategi...
Clément Viguier,Jean-Michel Mansuy,Guillaume Martin-Blondel
Clément Viguier
Purpose of review: Flaviviruses are an increasing public health concern, responsible for a broad spectrum of human disease ranging from asymptomatic or mild febrile illness to severe neuroinvasive infections such as encep...