Tiffany Wong,Joanne Yeung,Kyla J Hildebrand et al.
Tiffany Wong et al.
Purpose of review: There have been exciting recent advances in identifying new mutations that cause human primary immunodeficiencies which impact innate immune defences. In this review, we will highlight the most importan...
Recent advances in understanding and managing adenosine deaminase and purine nucleoside phosphorylase deficiencies [0.03%]
近期在腺苷脱氨酶和嘌呤核糖磷酸化酶缺乏症的研究和管理方面的新进展
Eyal Grunebaum,Amos Cohen,Chaim M Roifman
Eyal Grunebaum
Purpose of the review: To review the recent advances in the understanding and management of the immune and nonimmune effects of inherited adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP) deficiencies. ...
X-linked lymphoproliferative syndromes and related autosomal recessive disorders [0.03%]
X连锁淋巴增生综合征及相关的常染色体隐性遗传病
André Veillette,Luis-Alberto Pérez-Quintero,Sylvain Latour
André Veillette
Purpose of review: X-linked lymphoproliferative (XLP) syndromes and related autosomal disorders are severe primary immune deficiencies triggered by infection with Epstein-Barr virus (EBV), the causative agent of infectiou...
Joaquín Sastre
Joaquín Sastre
Purpose of review: To describe the recent insights of how molecular diagnosis can be useful to improve indication and selection of suitable allergens for specific immunotherapy and to increase its safety. ...
In-vivo confocal microscopy of the ocular surface: ocular allergy and dry eye [0.03%]
眼前节共焦显微镜在过敏性结膜炎及干眼中的应用
Edoardo Villani,Flavio Mantelli,Paolo Nucci
Edoardo Villani
Purpose of review: To summarize recent studies on in-vivo confocal microscopy (IVCM) findings in ocular allergy and dry eye disease (DED), highlighting the role of IVCM in the advancement of knowledge of these diseases. ...
The ocular surface epithelial barrier and other mechanisms of mucosal protection: from allergy to infectious diseases [0.03%]
结膜表面上皮屏障和其他黏膜保护机制：从过敏到传染病
Flavio Mantelli,Jerome Mauris,Pablo Argüeso
Flavio Mantelli
Purpose of review: Studies completed in the last decade provide new insights into the role of the epithelial glycocalyx in maintaining ocular surface barrier function. This review summarizes these findings, their relevanc...
Andrea Leonardi,Stefano Bonini
Andrea Leonardi
Purpose of review: The purpose of the present review is to provide an overview on the clinical features and long-term complications of severe ocular allergies, with a special focus on the corneal involvement observed in t...
Punchama Pacharn,Pakit Vichyanond
Punchama Pacharn
Purpose of review: Allergic conjunctivitis is an IgE-mediated inflammatory of conjunctiva. Despite the fact that histamine is a major mediator in this condition, use of topical antihistamines often gives only temporarily ...
Terrence P O&#x;Brien
Terrence P O&#x;Brien
Purpose of review: The focus of this review is to provide a logical paradigm for the diagnosis and treatment of ocular allergies, with a focus on seasonal allergic conjunctivitis (SAC) and perennial allergic conjunctiviti...