Improving machine-learning development in allergology: bridging the gap between open-access and cohort-based databases [0.03%]
改善过敏学中的机器学习开发：弥合开放获取与队列数据库之间差距的方法
Aleix Arnau-Soler,Jeremy Corriger,Yannick Chantran et al.
Aleix Arnau-Soler et al.
Purpose of review: The advent of high-throughput data generation and artificial intelligence has transformed allergy research. Open-access database (OAD) and cohort-based database (CBD) provide essential resources for mac...
Carlo Maria Rossi,Antonio di Sabatino
Carlo Maria Rossi
Purpose of review: Eosinophilic gastrointestinal disorders (EGID) are on the rise and impose a significant burden on patients. EGID other than eosinophilic esophagitis (EoE) remain diagnostically and therapeutically chall...
Amanda Morgan,Maeve G MacMurdo
Amanda Morgan
Purpose of review: Chronic beryllium disease (CBD) is a granulomatous lung disorder resulting from a cell-mediated immune response to beryllium exposure. Despite exposure regulations, new cases continue to emerge across b...
Markéta Bloomfield,Klára Šabatková,Zuzana Paračková
Markéta Bloomfield
Purpose of review: The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway is a central conduit linking cytokine signals to immune and tissue homeostasis. Over the past decade, a rapidly expan...
WHIM syndrome: from mechanism to targeted therapy - advances shaping clinical care [0.03%]
WHIM综合征：从发病机制到靶向治疗——影响临床实践的研究进展
Rahim Z Miller,Christoph B Geier,Jacob R Bledsoe et al.
Rahim Z Miller et al.
Purpose of review: Warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome is an autosomal dominant combined immunodeficiency (CID), often caused by increased CXCR4 pathway signaling. Against early-ons...
Stromal and immune cell interplay promotes neutrophilic inflammation in chronic rhinosinusitis with nasal polyps [0.03%]
间质和免疫细胞互作促进鼻息肉慢性鼻窦炎的中性粒细胞性炎症
Ruo-Yu Lu,Cui-Lian Guo,Zheng Liu
Ruo-Yu Lu
Purpose of review: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory disorder, with neutrophilic inflammation representing a clinically challenging endotype due to its resistance to cortico...
Callum Lewandrowski,Brian P Peppers,Chadi A Makary
Callum Lewandrowski
Purpose of review: This review provides the current understanding on primary antibody deficiencies (PAD) in children with chronic rhinosinusitis (CRS). Re...
Update on occupational contact urticaria: a systematic narrative review [0.03%]
职业性接触性荨麻疹的最新研究进展：系统叙述综述
Mojca Bizjak-Suran,Ingrid Løken Jørgensen,Jose Hernán Alfonso
Mojca Bizjak-Suran
Purpose of review: Occupational contact urticaria (OCU) is an immediate-type skin reaction triggered by chemicals or proteins encountered in the workplace. It is classified as either nonimmunologic (irritant) or immunolog...
Ekta Perera,Christopher Codispoti,Mahboobeh Mahdavinia
Ekta Perera
Purpose of review: This review examines how environmental injustice contributes to disparities in allergic diseases, including asthma, allergic rhinitis, and atopic dermatitis. It focuses on the role of social, geographic...
Callan Krevanko,Coralynn Sack
Callan Krevanko
Purpose of review: The expansion of the legal cannabis market has driven rapid, exponential growth in its workforce. Emerging evidence suggests that occupational exposures during cannabis production contribute to respirat...