Anti-interleukin 4 and 13 for asthma treatment in the era of endotypes [0.03%]
IL-4和IL-13阻断剂成为哮喘分型治疗的新利器
Andrew L Kau,Phillip E Korenblat
Andrew L Kau
Purpose of review: To summarize recent advances in IL-4 and IL-13 blockade in the treatment of asthma. Recent findings: Historically, a...
Seshi Manam,Teresa Tsakok,Stephen Till et al.
Seshi Manam et al.
Purpose of review: We conducted a systematic literature search for studies investigating the link between atopic dermatitis and food sensitization or clinically significant allergy (FA) in adults, to assess the strength o...
Implications of population structure and ancestry on asthma genetic studies [0.03%]
人口结构和祖先背景对哮喘遗传研究的影响
Victor E Ortega,Deborah A Meyers
Victor E Ortega
Purpose of review: The frequency and severity of asthma differ between different racial and ethnic groups. An understanding of the genetic basis for these differences could constitute future genetic biomarker panels for p...
Cockroach allergy and allergen-specific immunotherapy in asthma: potential and pitfalls [0.03%]
基于过敏的蟑螂特异性免疫疗法在哮喘中的应用：潜力与挑战
Gillian Bassirpour,Edward Zoratti
Gillian Bassirpour
Purpose of review: To provide a summary and discussion of cockroach allergy and clinical trials of cockroach allergen immunotherapy. Recent findings: ...
Specific immunotherapy and biological treatments for occupational allergy [0.03%]
职业性过敏的特异性免疫疗法和生物治疗
Gianna Moscato,Gianni Pala,Joaquin Sastre
Gianna Moscato
Purpose of review: Occupational allergy represents a substantial health, social, and financial burden for the society. Its management is a complex task that, in selected cases, may also include allergen-specific immunothe...
Harold S Nelson
Harold S Nelson
Purpose of review: Although systematic reviews have confirmed the effectiveness of subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) for the treatment of allergic rhinitis and allergic asthma, a review...
Paulo J Gomes
Paulo J Gomes
Purpose of review: This review describes recent findings and trends in prevalence and treatment of allergic ocular diseases. Although the major focus is on seasonal and perennial allergic conjunctivitis, related disorders...
Jillian L Barlow,Andrew N J McKenzie
Jillian L Barlow
Purpose of review: Recent decades have seen allergic diseases become endemic in a number of developed countries. Understanding the inflammatory processes that dictate these allergic responses is therefore important. ...
Nancy J Reyes,Daniel R Saban
Nancy J Reyes
Purpose of review: Ocular allergy is an IgE-mediated disease that results in inflammation of the conjunctiva and, in more severe cases, the cornea. This is driven by an immediate hypersensitivity response via mast cells, ...
The evolution of the hygiene hypothesis: the role of early-life exposures to viruses and microbes and their relationship to asthma and allergic diseases [0.03%]
卫生假说的演变：生命早期暴露于病毒和微生物与其与哮喘及过敏性疾病的关系
Denise Daley
Denise Daley
Purpose of review: Understanding the mechanisms involved in the development of asthma and allergic diseases is expanding, due in part to sequencing advances that have led to the identification of new viral strains such as...