Local allergic rhinitis: mechanisms, diagnosis and relevance for occupational rhinitis [0.03%]
局部过敏性鼻炎：机制，诊断及其在职业性鼻炎中的相关性
Francisca Gómez,Carmen Rondón,María Salas et al.
Francisca Gómez et al.
Purpose of review: Local allergic rhinitis (LAR) is a new form of allergic rhinitis that has caused a growing interest. The possibility of an occupational equivalent (occupational rhinitis) has not been yet explored. The ...
By the numbers: bringing new drugs for allergic/hypersensitivity diseases to the market [0.03%]
数字解读：过敏/超敏反应疾病新药上市情况
Pascal Demoly,Henry Milgrom
Pascal Demoly
Alessandro Fiocchi,Julie Wang
Alessandro Fiocchi
Four-year follow-up in children with moderate/severe uncontrolled asthma after withdrawal of a 1-year omalizumab treatment [0.03%]
奥马珠单抗治疗中重度难治性哮喘儿童4年随访研究
Carlos E Baena-Cagnani,Alvaro Teijeiro,G Walter Canonica
Carlos E Baena-Cagnani
Purpose of review: Allergic asthma, which is the most frequent asthma phenotype, is mainly a chronic inflammatory disease characterized by elevated serum IgE levels and specific-IgE against common allergens. A significant...
A review of biomarkers for predicting clinical reactivity to foods with a focus on specific immunoglobulin E antibodies [0.03%]
基于特异性免疫球蛋白E抗体预测食物临床反应生物标志物的评述
Sakura Sato,Noriyuki Yanagida,Kiyotaka Ohtani et al.
Sakura Sato et al.
Purpose of review: The purpose of this study is to assess the latest studies that focus on specific immunoglobulin (Ig)E antibodies for predicting clinical reactivity to foods. ...
Clinically relevant outcome measures for assessing disease activity, disease control and quality of life impairment in patients with chronic spontaneous urticaria and recurrent angioedema [0.03%]
慢性自发性荨麻疹和复发性血管性水肿患者疾病活动度、疾病控制及生活质量损害的临床相关结局指标评估措施
Karsten Weller,Torsten Zuberbier,Marcus Maurer
Karsten Weller
Purpose of review: The aim of this review is to highlight the most important, clinically relevant patient-reported outcome (PRO) measures for chronic spontaneous urticaria and recurrent angioedema. ...
Clinically relevant outcome measures for new pharmacotherapy, allergen avoidance and immunotherapy trials in allergic rhinoconjunctivitis [0.03%]
过敏性结膜炎新药治疗、避免接触过敏原及免疫疗法临床试验的相关结果测量指标
Oliver Pfaar,Ludger Klimek,Roy Gerth van Wijk
Oliver Pfaar
Purpose of review: The purpose of this review is to provide a current overview on both primary and secondary measures of efficacy of therapeutic interventions for clinical trials in allergic rhinoconjunctivitis (ARC) pati...
Clinically relevant outcome measures for new therapies of asthma using pharmaceutical and biologic agents [0.03%]
哮喘新药与生物制剂疗法的临床疗效评价指标
Louis-Philippe Boulet,Pascal Chanez
Louis-Philippe Boulet
Purpose of review: To determine the benefits of new asthma drugs or therapies, they should be assessed with regard to their effects on relevant clinical outcomes. ...
Clinically relevant outcome measures of novel pharmacotherapy for nonallergic rhinitis [0.03%]
用于非过敏性鼻炎新药治疗的临床相关结果测量标准
Kari R Brown,Jonathan A Bernstein
Kari R Brown
Purpose of review: The purpose of this review is to briefly provide the current understanding of the pathogenesis of nonallergic rhinitis (NAR), currently available pharmacotherapies as well as some recent advancement in ...
Food for thought: progress in understanding the causes and mechanisms of food allergy [0.03%]
值得思考的食物：食物过敏病因及机制研究进展
Sarah Ashley,Thanh Dang,Jennifer Koplin et al.
Sarah Ashley et al.
Purpose of review: The community burden of food allergy appears to be rising, yet the causes and mechanisms are not completely understood. The purpose of this review is to provide a snapshot of the state of play of IgE fo...