Hidden allergens and oral mite anaphylaxis: the pancake syndrome revisited [0.03%]
隐藏的过敏原和口腔螨过敏性休克：“薄饼综合征”再探讨
Mario Sánchez-Borges,Enrique Fernandez-Caldas
Mario Sánchez-Borges
Purpose of review: To present currently available information on oral mite anaphylaxis. Recent findings: Oral mite anaphylaxis (pancake...
Anna Sala-Cunill,Victoria Cardona
Anna Sala-Cunill
Purpose of review: The purpose of this study is to describe the current knowledge regarding mediators involved in anaphylactic reactions, with a special focus on key effector cells and mechanisms. ...
T Ted Song,Phil Lieberman
T Ted Song
Purpose of review: The purpose of this manuscript is to review the literature in support of epinephrine (adrenaline) as first line of therapy of anaphylaxis, not H-1 antihistamines or corticosteroids. ...
Katharine M Woessner
Katharine M Woessner
Purpose of review: The use of aspirin in coronary artery disease and address the unmet need of aspirin therapy in patients with history of hypersensitivity reactions to aspirin (acetylsalicylic acid; ASA) or other nonster...
Penicillin allergy: optimizing diagnostic protocols, public health implications, and future research needs [0.03%]
青霉素过敏：优化诊断流程、公共卫生影响及未来研究方向
Eric Macy
Eric Macy
Purpose of review: Unverified penicillin allergy is being increasingly recognized as a public health concern. The ideal protocol for verifying true clinically significant IgE-mediated penicillin allergy needs to use only ...
Yee Kiat Heng,Yen Loo Lim
Yee Kiat Heng
Purpose of review: Population ageing is a worldwide phenomenon. The presence of multiple comorbidities, polypharmacy, age-related changes in pharmacokinetics and pharmacodynamics, as well as skin changes in the elderly co...
Tetsuo Shiohara,Yoshiko Mizukawa,Yumi Aoyama
Tetsuo Shiohara
Purpose of review: Severe adverse drug reactions (ADRs) including Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) and drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and syste...
Genetic basis of hypersensitivity reactions to nonsteroidal anti-inflammatory drugs [0.03%]
非甾体抗炎药超敏反应的遗传学基础
Francisca Gómez,James R Perkins,Elena García-Martín et al.
Francisca Gómez et al.
Purpose of review: NSAIDs are the main triggers of hypersensitivity reactions to drugs. However, the full genetic and molecular basis of these reactions has yet to be uncovered. In this article, we have summarized researc...
José A G Agúndez,Cristobalina Mayorga,Elena García-Martin
José A G Agúndez
Purpose of review: The aim of the present review was to discuss recent advances supporting a role of drug metabolism, and particularly of the generation of reactive metabolites, in hypersensitivity reactions to drugs. ...
Drug hypersensitivity reactions: more basic and clinical research is needed [0.03%]
需要更多的基础和临床研究来解决药物过敏反应问题
Miguel Blanca,Bernard Y-H Thong
Miguel Blanca