Difficult-to-control asthma: epidemiology and its link with environmental factors [0.03%]
难治性哮喘的流行病学及其与环境因素的关系
William J Sheehan,Wanda Phipatanakul
William J Sheehan
Purpose of review: The aim of the present review was to discuss the epidemiology of inadequate asthma control with an examination of contributing environmental factors. ...
The genetics of the skin barrier in eczema and other allergic disorders [0.03%]
特应性皮炎及其他过敏性疾病中皮肤屏障的遗传学研究
Ingo Marenholz,Jorge Esparza-Gordillo,Young-Ae Lee
Ingo Marenholz
Purpose of review: We summarize current knowledge on the genetic determinants of skin barrier deficiency in relation to eczema and disease progression to other allergic manifestations. ...
Reaching clinically relevant outcome measures for new pharmacotherapy and immunotherapy of atopic eczema [0.03%]
寻找新的药物和免疫疗法治疗特应性皮炎的临床相关结果指标
Joanne Chalmers,Stefanie Deckert,Jochen Schmitt;Harmonising Outcome Measures for Atopic Dermatitis (HOME) Initiative Executive Board
Joanne Chalmers
Purpose of review: This article describes the core outcome set (COS) for atopic eczema trials. Recent findings: COS describe a minimum ...
Garry M Walsh
Garry M Walsh
Purpose of review: There is considerable evidence that implicates eosinophils as important effector cells in the inflammation characteristic of eosinophilic asthma. IL-5 is central to eosinophil maturation and release fro...
Yueh-Ying Han,Erick Forno,Fernando Holguin et al.
Yueh-Ying Han et al.
Purpose of review: Our objective was to provide an overview and discussion of recent experimental studies, epidemiologic studies, and clinical trials of diet and asthma. We focus on dietary sources and vitamins with antio...
Liliana Cifuentes
Liliana Cifuentes
Purpose of review: The purpose of this review is to provide a brief overview of the risks of consumption of bee products in honeybee venom allergic patients and compositae allergic patients, the potential allergens involv...
A 'difficult' insect allergy patient: reliable history of a sting, but all testing negative [0.03%]
一位“棘手”的昆虫过敏患者:被蜇后有过敏症状但所有检查结果均为阴性
James M Tracy,Jonathan A Olsen,John Carlson
James M Tracy
Purpose of review: Few conditions are as treatable as allergy to stinging insects, with venom immunotherapy (VIT) providing up to 98% protection to subsequent stings. The challenge with VIT is not in the treatment, but in...
Susan A Rudders,Carlos A Camargo Jr
Susan A Rudders
Purpose of review: The role of vitamin D in the development of food allergy is unclear. We summarize recent data on the epidemiologic link between sunlight (UVB) and food allergy, and evidence for and against a specific r...
Anaphylaxis in adolescents: a potential tripartite management framework [0.03%]
青少年过敏性休克的潜在三相管理模式框架研究
Bright I Nwaru,Aziz Sheikh
Bright I Nwaru
Purpose of review: The incidence of anaphylaxis is increasing across all ages, but the risk of morbidity and fatality is disproportionately high in adolescents. This may, at least in part, be a consequence of a constellat...