Current risks of byssinosis and chronic obstructive pulmonary disease in textile workers [0.03%]
纺织工人目前患棉尘症和慢性阻塞性肺病的风险
Asaad Ahmed Nafees,Paul Cullinan
Asaad Ahmed Nafees
Purpose of review: The textile manufacturing sector is a major contributor to the economies of several emergent economies in the global South. Respiratory disease, including byssinosis and chronic obstructive pulmonary di...
Precision medicine and choosing a biologic in asthma: understanding the current state of knowledge for predictors of response and clinical remission [0.03%]
精准医学与哮喘生物制剂的选择：了解目前针对缓解效果和临床治愈的预测因子的知识状态
Sadhana Balasubramanyam,Elizabeth K George,Eileen Wang
Sadhana Balasubramanyam
Purpose of review: We review updated key literature on comparative meta-analyses and real-world effectiveness of asthma biologics, with a focus on predictors of response and clinical remission while highlighting ongoing k...
Exploring the management of recurrent angioedema caused by different mechanisms [0.03%]
探究由不同机制引发的反复发作性血管水肿的治疗与管理方法
Ilaria Mormile,Chiara Suffritti,Maria Bova
Ilaria Mormile
Purpose of review: We aim to explore the most recent insights into the pathogenesis of recurrent angioedema caused by different mechanisms and then focus on the management and treatment approaches available. ...
Alisa Pham,Rose Corcoran,Dinah Foer
Alisa Pham
Purpose of review: This review summarizes recent basic, translational, and clinical research on type 2 diabetes (T2D) and its relationship with asthma severity in the context of T2D mechanisms and asthma outcomes. ...
Isao Suzaki
Isao Suzaki
Purpose of review: Chronic rhinosinusitis (CRS) is a heterogeneous condition, so personalized treatment based on each patient's pathophysiology is essential, rather than a one-size-fits-all approach. Drug therapy for CRS ...
Paucity of gastrointestinal plasma cells in common variable immunodeficiency [0.03%]
常见变量免疫缺陷患者胃肠道浆细胞缺乏
Jan Willem N Marsden,Miangela M Laclé,Mirjam Severs et al.
Jan Willem N Marsden et al.
Purpose of review: Common variable immunodeficiency enteropathy (CVID-E) is a noninfectious complication of CVID caused by chronic inflammation of the gastrointestinal (GI) tract. Based on literature, a paucity or lack of...
Update on hereditary C1q deficiency: pathophysiology, clinical presentation, genotype and management [0.03%]
补体C1Q遗传性缺陷的最新研究进展：发病机制、临床表现、基因型和治疗管理
Helena Buso,Clément Triaille,Aisling M Flinn et al.
Helena Buso et al.
Purpose of review: C1q deficiency is a rare inborn error of immunity characterized by susceptibility to severe infections and profound immune dysregulation, with a systemic lupus erythematosus-like phenotype. The manageme...
STAT1 and STAT3 gain of function: clinically heterogenous immune regulatory disorders [0.03%]
STAT1和STAT3功能增强：异质性免疫调节障碍
Peter Olbrich,Alexandra F Freeman
Peter Olbrich
Purpose of review: The identification of STAT1 gain-of-function (GOF) in 2011 and STAT3 GOF in 2014 has advanced our understanding of the host immunity along the JAK/STAT pathway and allowed targeted treatment approaches....
Expanding the spectrum of IPEX: from new clinical findings to novel treatments [0.03%]
从新的临床发现到新型治疗方法：IPEX综合征的研究进展
Marta Voarino,Filippo Consonni,Eleonora Gambineri
Marta Voarino
Purpose of review: This review aims to provide an overview of recent research findings regarding immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, focusing on clinical and immunological nove...
New mechanisms in diisocyanate-mediated allergy/toxicity: are microRNAs in play? [0.03%]
二异氰酸酯介导过敏/毒性新机制：微小核糖核酸在起作用吗？
Chen-Chung Lin,Brandon F Law,Justin M Hettick
Chen-Chung Lin
Purpose of review: To describe recent findings of diisocyanate-mediated mechanisms in allergy and toxicology by addressing the role of microRNA (miR) in immune responses that may contribute to the development of occupatio...