Comparing hemophagocytic lymphohistiocytosis in pediatric and adult patients [0.03%]
儿童及成人患者中郎格汉斯细胞组织细胞增生症的对比研究
Christian A Wysocki
Christian A Wysocki
Purpose of review: Hemophagocytic lymphohistiocytosis (HLH) has long been thought of primarily as a pediatric disease. However, this syndrome may occur secondary to underlying malignancies, infections, and autoimmune dise...
Whole exome sequencing in inborn errors of immunity: use the power but mind the limits [0.03%]
全外显子组测序在先天性免疫缺陷中的应用：充分利用但也要注意其局限性
Giorgia Bucciol,Erika Van Nieuwenhove,Leen Moens et al.
Giorgia Bucciol et al.
Purpose of review: Next-generation sequencing, especially whole exome sequencing (WES), has revolutionized the molecular diagnosis of inborn errors of immunity. This review summarizes the generation and analysis of next-g...
Hjalte H Andersen,Gil Yosipovitch,Anat Galor
Hjalte H Andersen
Purpose of review: This review aims to describe the recent findings on epidemiology, pathophysiology, and management of neuropathic symptoms of the ocular surface, with a focus on potential similarities between sensations...
When nutrition and allergy collide: the rise of anaphylaxis to plant foods [0.03%]
营养与过敏的碰撞：植物食物引起的过敏性休克增多现象
Isabel J Skypala
Isabel J Skypala
Purpose of review: Interest in nutrition is increasing, but in the world of internet health gurus, whilst the nutritional benefits of fruits and vegetables are extolled, wheat is often vilified. This review will assess th...
Novel molecular defects associated with very early-onset inflammatory bowel [0.03%]
与极早期发作的炎症性肠病相关的新型分子缺陷
Sara Ciullini Mannurita,Eleonora Gambineri
Sara Ciullini Mannurita
Purpose of review: Immune dysregulation disorders present with common clinical features of multiorgan autoimmunity. Gastrointestinal involvement is the hallmark of an impaired immune homeostasis. This review will give an ...
Hymenoptera-induced anaphylaxis: is it a mast cell driven hematological disorder? [0.03%]
hymenoptera诱发的过敏性休克：它是mast细胞引起的血液系统疾病吗？
Knut Brockow,Cem Akin
Knut Brockow
Purpose of review: Hymenoptera-induced allergy (HVA) is a common cause of anaphylaxis and may be fatal. It is associated with systemic mastocytosis in about 7% of adult patients. Systemic mastocytosis is a proliferative d...
Ocular surface lubricants [0.03%]
眼部表面润滑剂
Leonard Bielory,Preeti Wagle
Leonard Bielory
Purpose of review: The purpose of this article is to provide an overview of the ocular lubricants currently available, consider the components of the various formulations and highlight the status of preservative use in th...
Climate changes and Hymenoptera venom allergy: are there some connections? [0.03%]
气候变化与膜翅目昆虫毒液过敏：它们之间存在某些联系吗？
Stefano Turillazzi,Francesco Turillazzi
Stefano Turillazzi
Purpose of review: This review aims to update the world status of the main allergenic stinging Hymenoptera. Recent findings: In this re...
Peter K Smith
Peter K Smith
Purpose of review: The aim of this study was to appraise the evidence relating to dietary advanced glycation end-products (AGEs), their influence on innate and adaptive immune responses and their possible role in the incr...
Thilo Jakob,Ulrich Müller,Arthur Helbling et al.
Thilo Jakob et al.
Purpose of review: Component-resolved diagnostics makes use of defined allergen molecules to analyse IgE-mediated sensitizations at a molecular level. Here, we review recent studies on the use of component-resolved diagno...