Evidence establishing a link between prenatal and early-life stress and asthma development [0.03%]
证实孕期和早期生活压力与哮喘发病之间关系的证据
Maria José Rosa,Alison G Lee,Rosalind J Wright
Maria José Rosa
Purpose of review: The objective of this review is to provide an update on our evolving understanding of the effects of stress in pregnancy and during early development on the onset of asthma-related phenotypes across chi...
Anne E Wyman,Stella E Hines
Anne E Wyman
Purpose of review: Occupational and environmental exposures to metals can result in multiple pulmonary conditions. This article will review recent epidemiologic and mechanistic studies that have enhanced our understanding...
Santiago Quirce,Darío Antolín-Amérigo,Javier Domínguez-Ortega
Santiago Quirce
Purpose of review: With the development of innovative technologies, new agents are continually introduced to the workplace. Some of these agents can act as hidden allergens whenever they are not declared in the product la...
Asthma versus chronic obstructive pulmonary disease, the Dutch versus British hypothesis, and role of interleukin-5 [0.03%]
哮喘与慢性阻塞性肺病、荷兰学说与英国学说以及白细胞介素-5的作用
Jeffrey M Chambliss,Sanjiv Sur,Julia W Tripple
Jeffrey M Chambliss
Purpose of review: Asthma and COPD represent heterogeneous disorders with broad ranging impact on patients and health systems. This review focuses on evidence for early attempts at understanding their pathogenesis by the ...
Giorgio W Canonica,Matteo Ferrando,Ilaria Baiardini et al.
Giorgio W Canonica et al.
Purpose of review: In this review, we herein describe the progress in management of severe asthma, evolving from a 'blockbuster approach' to a more personalized approach targeted to the utilization of endotype-driven ther...
Adil S Zahiruddin,J Andrew Grant,Sanjiv Sur
Adil S Zahiruddin
Purpose of review: Although asthma is a common disease worldwide, its pathogenesis remains to be fully elucidated. There is increasing evidence of the interaction between epigenetics, DNA-damage, and environmental allerge...
Association between allergic and nonallergic rhinitis and obstructive sleep apnea [0.03%]
变应性和非变应性鼻炎与阻塞性睡眠呼吸暂停的关系
Ming Zheng,Xiangdong Wang,Luo Zhang
Ming Zheng
Purpose of review: Allergic rhinitis and nonallergic rhinitis (NAR) are common disorders, which have been considered as potential risk factors for obstructive sleep apnea (OSA). This review summarizes the proposed underly...
Prevalence and clinical characteristics of local allergic rhinitis to house dust mites [0.03%]
居家尘螨引起的局部过敏性鼻炎的流行率和临床特征
Yoo Seob Shin,Chang-Gyu Jung,Hae-Sim Park
Yoo Seob Shin
Purpose of review: Local allergic rhinitis (LAR) is a recently classified subtype of rhinitis defined by a nasal allergic response in patients without systemic evidence of atopy. Recent studies have reported the prevalenc...
Sveva Castelli,Stefania Arasi,Ruby Pawankar et al.
Sveva Castelli et al.
Purpose of review: The identification of immunological markers in nasal secretions and tears is becoming essential in the study of allergic diseases. The collection procedure of nasal and ocular secretions directly influe...
Pedro Giavina-Bianchi,Marcelo V Aun,Jorge Kalil
Pedro Giavina-Bianchi
Purpose of review: The present review addresses the epidemiology, analyzes the current data and promotes global awareness of drug-induced anaphylaxis. Rec...