Jonny Peter,Phuti Choshi,Rannakoe J Lehloenya
Jonny Peter
Purpose of review: Immune-mediated adverse drug reactions (IM-ADRs) are many times more common in HIV-infected patients. Usual offending drugs include antiretroviral and antiinfectives, but the burden of specific drug IM-...
Knut Brockow,Wolfgang Pfützner
Knut Brockow
Purpose of review: Cutaneous drug hypersensitivity reactions (CDHRs) are a complicated area with multiple clinical manifestations and differential diagnoses, requiring differentiated diagnostic measurements and optimized ...
Enrico Heffler,Luca Malvezzi,Francesca Pirola et al.
Enrico Heffler et al.
Purpose of review: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex inflammatory sinonasal disease that deserves a multidisciplinary precision medicine approach. In a precision medicine model, a more pragmat...
E Gómez,M Ruano,M L Somoza et al.
E Gómez et al.
Purpose of review: Nonimmediate drug hypersensitivity reactions (NI-DHR) constitute the most complex group of drug allergy, with many drugs involved. Both parent drugs and their reactive metabolites can be implicated. Alt...
Nonhlanhla Lunjani,Carol Hlela,Liam OMahony
Nonhlanhla Lunjani
Purpose of review: The skin is home to a diverse milieu of bacteria, fungi, viruses, bacteriophages, and archaeal communities. The application of culture-independent approaches has revolutionized the characterization of t...
New phenotypes in hypersensitivity reactions to nonsteroidal anti-inflammatory drugs [0.03%]
非甾体抗炎药过敏反应的新表型
Youngsoo Lee,Yoo Seob Shin,Hae-Sim Park
Youngsoo Lee
Purpose of review: Nonsteroidal anti-inflammatory drug (NSAID) is one of the most frequently prescribed medications in the medical field, and hypersensitivity to NSAID is a common adverse drug reaction encountered. Howeve...
Chengshuo Wang,Luo Zhang
Chengshuo Wang
Purpose of review: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory condition with different endotypes between patients from eastern or western countries. Targeted biologics are currently ...
Yury Zhernov,Mirela Curin,Musa Khaitov et al.
Yury Zhernov et al.
Purpose of review: More than 30 years ago, the first molecular structures of allergens were elucidated and defined recombinant allergens became available. We review the state of the art regarding molecular AIT with the go...
Eosinophilic esophagitis during sublingual and oral allergen immunotherapy [0.03%]
舌下和口服过敏免疫治疗过程中的嗜酸性食管炎
Joseph Cafone,Peter Capucilli,David A Hill et al.
Joseph Cafone et al.
Purpose of review: The aim of this review is to discuss the current evidence regarding the development of eosinophilic esophagitis (EoE) in individuals undergoing oral and sublingual immunotherapy (SLIT) for both food and...
Luciana Kase Tanno,Alberto Alvarez-Perea,Guillaume Pouessel
Luciana Kase Tanno
Purpose of review: Anaphylaxis is a recognized cause of death in all ages, which requires prompt recognition and treatment. We here propose to review the current and new pharmacological treatment of anaphylaxis in the vie...