Biological agents for severe asthma: the evolution of the at-home self-injection approach [0.03%]
重度哮喘的生物制剂：居家自我注射疗法的发展演变路径
Carlo Lombardi,Diego Bagnasco,Giovanni Passalacqua
Carlo Lombardi
Purpose of review: New biological agents, in addition to the well-established omalizumab, have been nowadays introduced into clinical practice for severe asthma. This suggested the possibility of an at-home self-administr...
Pharmacotherapy in allergy medicine: from 'ipse dixit' to the evidence-based medicine [0.03%]
过敏性疾病药物治疗的发展：从个人经验到循证医学
Maurizio Mennini,Stefania Arasi,Lamia Dahdah et al.
Maurizio Mennini et al.
Purpose of review: The aim of the article is to examine the contributions made in recent years by evidence-based medicine to the understanding, positioning, and use of drugs for the treatment of the main allergic conditio...
β-Blockers and angiotensin-converting enzyme inhibitors with sublingual immunotherapy: are risks related to individual product safety profile? [0.03%]
β受体阻滞剂和血管紧张素转换酶抑制剂与舌下免疫治疗：风险与个体产品安全配置有关吗？
Derek M Smith,Christopher A Coop,Theodore M Freeman
Derek M Smith
Purpose of review: The objective of this article is to review the available literature regarding the risks associated with sublingual immunotherapy and angiotensin-converting enzyme (ACE) inhibitors or β-blocker use. It ...
Urticaria and the gut [0.03%]
肠病学与荨麻疹
Chia-Yu Chu,Torsten Zuberbier
Chia-Yu Chu
Purpose of review: To review recent evidence on the association of urticaria and the gut diseases, focusing on the roles of chronic inflammation with or without Helicobacter pylori (H. Pylori) infection. ...
The clinical impact of cross-reactions between allergens on allergic skin diseases [0.03%]
过敏原交叉反应在过敏性皮肤病的临床影响
Karin Hoffmann-Sommergruber,Lennart M Roesner
Karin Hoffmann-Sommergruber
Purpose of review: The route of allergen sensing via the skin appears to influence the immune system towards mounting a type 2 response, especially in genetically predisposed individuals. Allergens recognized this way may...
The role of IL-17, IL-23 and IL-31, IL-33 in allergic skin diseases [0.03%]
IL-17、IL-23、IL-31和IL-33在过敏性皮肤病中的作用
Fatih A Topal,Torsten Zuberbier,Michael P Makris et al.
Fatih A Topal et al.
Purpose of review: Allergic skin diseases such as urticaria, atopic dermatitis and allergic contact dermatitis are among the most common skin diseases with severe socioeconomic consequences. The pathogenesis of allergic s...
Immediate hypersensitivity reactions to steroids and steroid containing medications [0.03%]
激素及含激素药物的即刻过敏反应
Krzysztof Rutkowski,Annette Wagner,Ryszard Rutkowski
Krzysztof Rutkowski
Purpose of review: Although rare and counterintuitive, hypersensitivity reactions to corticosteroids have been reported since the 1950s. Delayed hypersensitivity reactions following cutaneous exposure (contact allergy) ar...
Adverse reactions to vancomycin and cross-reactivity with other antibiotics [0.03%]
万古霉素的不良反应及其与其他抗生素的交叉过敏反应
Joseph F De Luca,Natasha E Holmes,Jason A Trubiano
Joseph F De Luca
Purpose of review: Glycopeptide antibiotics such as vancomycin are frequently utilized to treat resistant Gram-positive infections such as methicillin-resistant Staphylococcus aureus. The current literature on glycopeptid...
Andrea Matucci,Alessandra Vultaggio,Francesca Nencini et al.
Andrea Matucci et al.
Purpose of review: This review summarizes the current knowledge of the pathogenic mechanisms of biologics-induced anaphylaxis, and the diagnostic and prophylactic strategies in the management of potentially reactive patie...
Birgitte Louise Bech Melchiors,Lene Heise Garvey
Birgitte Louise Bech Melchiors
Purpose of review: The purpose of this review is to provide an update on how best to manage the investigation of suspected perioperative hypersensitivity reactions based on recent literature and key publications. ...