Noriyuki Yanagida,Sakura Sato,Motohiro Ebisawa
Noriyuki Yanagida
Purpose of review: The oral food challenge (OFC) remains the cornerstone procedure for diagnosing food allergies and guiding patient management. Recently, stepwise OFC, a new management strategy starting with very-low-dos...
Heat generation and thermal safety of powered instrumentation in endoscopic sinus surgery [0.03%]
内窥镜鼻窦手术中电动器械的发热及安全性研究
Farah Dayana Zahedi,Pongsakorn Tantilipikorn,Baharudin Abdullah
Farah Dayana Zahedi
Purpose of review: This narrative review aims to summarize current evidence on thermal energy generation during endoscopic sinus surgery (ESS), with particular emphasis on the powered devices, their safe application, and ...
Biologics for chronic rhinosinusitis with nasal polyps: from downstream cytokine blockade to upstream epithelial targets [0.03%]
慢性鼻窦炎和鼻息肉的生物制剂治疗:从下游细胞因子阻断到上游上皮靶点
Farah Dayana Zahedi,Baharudin Abdullah,Pongsakorn Tantilipikorn
Farah Dayana Zahedi
Purpose of review: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogenous inflammatory disease that often persist despite optimal medical and surgical treatment. Advances in the understanding of CRS immunopat...
Skin intervention for food allergy prevention: recent advances and clinical implications [0.03%]
皮肤干预预防食物过敏:近期研究进展及临床意义
Kiwako Yamamoto-Hanada
Kiwako Yamamoto-Hanada
Purpose of review: Food allergy has increased globally, with infancy representing a critical window for prevention. Accumulating evidence has shifted attention toward the skin as a key route of allergen exposure, particul...
Botulinum toxin for allergic rhinitis: a systematic review and meta-analysis of its therapeutic potential [0.03%]
肉毒杆菌毒素治疗过敏性鼻炎:系统评价和荟萃分析
Eric Tan Jin Wee,Yee Cheng Kueh,Norhafiza Mat Lazim et al.
Eric Tan Jin Wee et al.
Purpose of review: Botulinum toxin type A (BTX-A) is emerging as a promising intervention for refractory allergic rhinitis. This study evaluates its effectiveness in treating refractory allergic rhinitis. ...
Basophil activation test in food allergy: where are we now? [0.03%]
食物过敏中的 basophil 激活试验:我们目前处于什么位置?
Malgorzata Niegowska,Rocco Luigi Valluzzi,Stefania Arasi
Malgorzata Niegowska
Purpose of review: To highlight the most recent findings on the basophil activation test (BAT) in food allergy, with a focus on advances in assay standardization and logistics, and on emerging clinical applications across...
Effect of platelet-rich plasma on surgical outcomes in chronic rhinosinusitis with nasal polyps: a systematic review and meta-analysis [0.03%]
富血小板血浆对鼻息肉型慢性鼻窦炎手术疗效影响的系统评价和meta分析
Linger Sim,Thevagi Maruthamuthu,Khairudin Abdullah et al.
Linger Sim et al.
Purpose of review: This review evaluates the current evidence on the effectiveness of platelet-rich plasma (PRP) as an adjuvant therapy to endoscopic sinus surgery (ESS) in adults with chronic rhinosinusitis with nasal po...
Reframing paucigranulocytic asthma through genetic endotyping: a hypothesis-generating focus on the 17q21 rs7216389 locus [0.03%]
通过遗传分型重塑嗜酸性粒细胞减少的哮喘患者:针对17q21 rs7216389位点的假说生成式研究焦点
Remo Poto,Rory Chan,Daniela Breda et al.
Remo Poto et al.
Purpose of review: Non-T2 asthma is currently defined by missing parameters, such as low blood eosinophils and FeNO, rather than positively identifiable mechanistic features. This definition overlaps with paucigranulocyti...
Improving machine-learning development in allergology: bridging the gap between open-access and cohort-based databases [0.03%]
改善过敏学中的机器学习开发:弥合开放获取与队列数据库之间差距的方法
Aleix Arnau-Soler,Jeremy Corriger,Yannick Chantran et al.
Aleix Arnau-Soler et al.
Purpose of review: The advent of high-throughput data generation and artificial intelligence has transformed allergy research. Open-access database (OAD) and cohort-based database (CBD) provide essential resources for mac...
Carlo Maria Rossi,Antonio di Sabatino
Carlo Maria Rossi
Purpose of review: Eosinophilic gastrointestinal disorders (EGID) are on the rise and impose a significant burden on patients. EGID other than eosinophilic esophagitis (EoE) remain diagnostically and therapeutically chall...