Nucleic acid vaccines and CpG oligodeoxynucleotides for allergen immunotherapy [0.03%]
核酸疫苗和CpG寡核苷酸用于过敏免疫疗法
Alain Jacquet
Alain Jacquet
Purpose of review: Molecular forms of allergen-specific immunotherapy (AIT) are continuously emerging to improve the efficacy of the treatment, to shorten the duration of protocols and to prevent any side effects. The pre...
Comparison of structural components and functional mechanisms within the skin vs. the conjunctival surface [0.03%]
皮肤与结膜表面的结构成分及功能机制比较分析
Lauren Valentine,Matthew R Norris,Leonard Bielory
Lauren Valentine
Purpose of review: The purpose of this review is to highlight and compare the structural and functional differences between the ocular surface and the skin. The goal is to further understand how these components interact ...
Assessment of receptor affinities of ophthalmic and systemic agents in dry eye disease [0.03%]
干眼病的眼科和全身用药受体亲和力评估
Patrick Janeczko,Matthew R Norris,Leonard Bielory
Patrick Janeczko
Purpose of review: To explore our current understanding of receptor profiles acted upon by medications used to treat dry eye disease (DED). Recent finding...
Basophil activation test in food allergy: is it ready for real-time? [0.03%]
basophil活化试验在食物过敏中的应用：是否已经准备就绪？
Tarun Keswani,Sarita U Patil
Tarun Keswani
Purpose of review: Utilization of basophil activation in the diagnosis and monitoring of food allergy has gained increasing recognition. An ex-vivo functional assay, basophil activation reflects clinical reactivity, there...
Sivanne Mendelson,Jaime Quintanilla,Matthew R Norris et al.
Sivanne Mendelson et al.
Purpose of review: Allergic rhinoconjunctivitis is one of the most common ocular surface allergic inflammatory conditions seen in primary care that impacts patient's quality of life. Allergic conjunctivitis is increasingl...
Anaphylaxis and Coronavirus Disease 2019 vaccine: a danger relationship? [0.03%]
过敏和新型冠状病毒疾病2019疫苗：一种危险的关系吗？
Luciana Kase Tanno,Mariana Castells,Marco Caminati et al.
Luciana Kase Tanno et al.
Purpose of review: Anaphylactic reactions reported after Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) RNA vaccines were expected to be more frequent in atopic subjects and attributed to its polyethylene gly...
Arianna Cafarotti,Alessandro Fiocchi,Stefania Arasi
Arianna Cafarotti
Purpose of review: To provide the most recent insights in the use of biologicals in the treatment of patients with anaphylaxis. Recent findings: ...
Aram Anto,Bernardo Sousa-Pinto,Jean Bousquet
Aram Anto
Purpose of review: Digital medicine (mHealth) aims to help patients and healthcare providers (HCPs) improve and facilitate the provision of patient care. It encompasses equipment/connected medical devices, mHealth service...
Mast cell activation syndrome: is anaphylaxis part of the phenotype? A systematic review [0.03%]
mast细胞活化综合征：过敏反应是其表型的一部分吗？系统综述
Vito Sabato,Moïse Michel,Ulrich Blank et al.
Vito Sabato et al.
Purpose of review: Mast cell activation syndrome (MCAS) and anaphylaxis are the result of a spontaneous or triggered pathological degranulation of mast cells (MCs) and might have as substrate normal or pathological MCs (i...
Anna Sala-Cunill,Victoria Cardona
Anna Sala-Cunill
Purpose of review: The purpose of the review is to identify unmet needs in the management of anaphylaxis, covering aspects such as epidemiology, diagnosis, treatment and prevention. ...