Hao Tseng,Robert A Wood
Hao Tseng
Purpose of review: Omalizumab was approved by the U.S. Food and Drug Administration (FDA) to reduce allergic reactions from accidental exposures to food allergens in 2024. This review examines the current state of play in...
Pregnancy complications in women with an inborn error of immunity: a systematic review [0.03%]
遗传性免疫缺陷女性的妊娠并发症：系统评价研究
Bengisu Yakut,Anna C R Knaapen,Xin Yu Cui et al.
Bengisu Yakut et al.
Purpose of review: Many patients with inborn errors of immunity (IEI) reach the reproductive age these days. This systematic review focuses on possible complications during pregnancy in women with IEI. ...
Upper gastrointestinal tract manifestations in primary antibody deficiencies: from Helicobacter pylori to gastric cancer [0.03%]
原发性抗体缺陷病的上消化道表现：从幽门螺旋杆菌感染到胃癌
Germano Sardella,Isabella Quinti,Federica Pulvirenti
Germano Sardella
Purpose of review: Gastric cancer has emerged as a prominent cause of mortality in individuals with primary antibody deficiencies (PAD), especially common variable immunodeficiency (CVID), however its pathogenesis remains...
When immunity turns rogue: lymphoma and lymphoproliferative disorders in common variable immune deficiency [0.03%]
当免疫力失控时：常见变量免疫缺陷相关的淋巴瘤和淋巴增生性疾病
Bianca Sciacca,Marianna Franco,Giulia Gualtiero et al.
Bianca Sciacca et al.
Purpose of review: The purpose of this review is to describe the most recent findings regarding lymphoma and lymphoproliferative disorders (LPDs) in common variable immune deficiency (CVID) patients, presenting epidemiolo...
Safa Baris
Safa Baris
Purpose of review: CTLA4-related immune disorders are primary immune dysregulation characterized by susceptibility to infections, autoimmunity, hyperinflammation, and malignancies. As new insights into their molecular mec...
DOCK8 deficiency [0.03%]
DOCK8缺陷症
Andrew R Gennery,Michael H Albert
Andrew R Gennery
Purpose of review: Previously described as an autosomal recessive form of hyper IgE syndrome, DOCK8 deficiency is now recognized as a combined immunodeficiency, with predominant dermatological manifestations. This review ...
Francesco Catamerò,Simona Barbaglia,Enrico Heffler et al.
Francesco Catamerò et al.
Purpose of review: This review explores patients' perspective on allergen immunotherapy (AIT) for respiratory allergy, addressing awareness, motivations, adherence challenges, perceived benefits and risks, and the importa...
Epinephrine nasal spray for the treatment of anaphylaxis: perspectives in pediatrics [0.03%]
儿科治疗过敏性休克的肾上腺素鼻喷雾剂：展望
Giada Crescioli,Mattia Giovannini,Benedetta Pessina et al.
Giada Crescioli et al.
Purpose of review: Anaphylaxis is a severe allergic reaction characterized by a rapid onset and can be potentially life-threatening. Epinephrine is considered the first-line treatment, and until recently, it was available...
Edoardo Cavaglià,Maurizio Marogna,Giovanni Paoletti et al.
Edoardo Cavaglià et al.
Purpose of review: This review evaluates the evidence on the effects of allergen immunotherapy (AIT) on lung function in asthma, with a focus on long-term outcomes. The topic is timely given the increasing interest in dis...
Josefine Gradman,Susanne Halken
Josefine Gradman
Purpose of review: The potential of allergen immunotherapy (AIT) to prevent allergic airway disease progression are demonstrated. Though not all patients benefit equally, there is limited research on which patients may be...