Lana Mukharesh,Wanda Phipatanakul,Jonathan M Gaffin
Lana Mukharesh
Purpose of review: Asthma is the most common chronic disease of childhood. Environmental exposures, such as allergens and pollutants, are ubiquitous factors associated with asthma development and asthma morbidity. In this...
Steven Ronsmans,Nicole Le Moual,Orianne Dumas
Steven Ronsmans
Purpose of review: In this narrative review, we aim to highlight novel research findings on both acute/subacute irritant-induced asthma (IIA) and chronic exposure IIA (also called 'low dose' IIA). ...
Andre E Espaillat,Michelle L Hernandez,Allison J Burbank
Andre E Espaillat
Purpose of review: Social determinants of health play a major role in healthcare utilization and outcomes in patients with asthma. Continuing to understand how these complex and interwoven relationships interact to impact...
Martina Votto,Riccardo Castagnoli,Gian Luigi Marseglia et al.
Martina Votto et al.
Purpose of review: This review summarizes current evidence on the potential link between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and autoimmunity. ...
Timothy P Moran
Timothy P Moran
Purpose of review: The increasing global prevalence of food allergy indicates that environmental exposures are likely contributing to food allergy development. This review summarizes recent studies on how specific factors...
Environment and the development of severe asthma in inner city population [0.03%]
环境与城市居民重症哮喘的发病机制及防治措施
Julia X Lee,Wanda Phipatanakul,Jonathan M Gaffin
Julia X Lee
Purpose of review: Higher asthma prevalence and morbidity are seen in inner-city areas, disproportionately affecting low-income families living in substandard housing. Children within these families experience more freque...
Riccardo Castagnoli,Ilaria Brambilla,Michele Miraglia Del Giudice et al.
Riccardo Castagnoli et al.
Purpose of review: This review aims to provide paediatricians with novel concepts from scientific evidence applicable to treating children with asthma. The latest guideline updates on paediatric asthma are discussed here,...
Hani Harb,Talal A Chatila
Hani Harb
Purpose of review: This review addresses recent progress in our understanding of the role of regulatory T (Treg) cells in enforcing immune tolerance and tissue homeostasis in the lung at steady state and in directing the ...
Gene therapy for inborn error of immunity - current status and future perspectives [0.03%]
基因治疗免疫系统先天错误-现状与未来展望
Anne Mudde,Claire Booth
Anne Mudde
Purpose of review: Development of hematopoietic stem cell (HSC) gene therapy (GT) for inborn errors of immunity (IEIs) continues to progress rapidly. Although more patients are being treated with HSC GT based on viral vec...
Giuseppe Guida,Vitina Carriero,Francesca Bertolini et al.
Giuseppe Guida et al.
Purpose of review: Exhaled nitric oxide (FENO) is a noninvasive marker of eosinophilic airway inflammation, therefore, highly informative in asthma. Although FENO measurement is a potentially accessible tool to many physi...