Where eye meets body part 1: uniting allergy pathways in ocular and nasal disease - IgE on the offense [0.03%]
从眼到鼻腔：联合过敏通路（IgE的进攻）（一）
Sebastian Borges,Victoria A Pereira,Christopher Chang et al.
Sebastian Borges et al.
Purpose of review: This review explores the shared immunologic mechanisms and clinical distinctions between seasonal and perennial allergic rhinitis (SAR, PAR) and their ocular counterparts, seasonal and perennial allergi...
Paula Galvan-Blasco,Javier Pereira-Gonzalez,Victoria Cardona
Paula Galvan-Blasco
Purpose of review: The rising incidence of anaphylaxis and reports of cases unresponsive to standard epinephrine treatment highlight the relevance of refractory anaphylaxis. There is a lack of standardized management prot...
Where eye meets body part 2: uniting allergy pathways in ocular and atopic disease - T cells take the lead [0.03%]
着眼体表第二部分：连接眼和特应性疾病的过敏途径-T细胞占主导地位
Sebastian Borges,Victoria A Pereira,Christopher Chang et al.
Sebastian Borges et al.
Purpose of review: This review compares the T-cell-mediated pathways of atopic dermatitis and atopic keratoconjunctivitis (AKC), as well as allergic asthma and vernal conjunctivitis (VKC).These chronic, T cell-mediated co...
Riham Shawer,Abraham Solomon
Riham Shawer
Purpose of review: This review's objective is to give readers an update on recent and developing information about the function of the ocular surface microbiome in keratoconus. ...
Biologic and small molecule therapies in chronic spontaneous urticaria: an update [0.03%]
慢性自发性荨麻疹的生物制剂和小分子药物治疗：最新进展
Bettina Wedi
Bettina Wedi
Purpose of review: Many new treatment options for chronic spontaneous urticaria have been clinically tested in recent years. This narrative review presents the current status of substances furthest along in development. ...
Mona-Rita Yacoub,Arianna Ferlito,Eustachio Nettis
Mona-Rita Yacoub
Purpose of review: This review provides an updated overview of the association between chronic urticaria (CU) and autoinflammatory syndromes (AS), underlining the diagnostic and therapeutic implications of identifying CU ...
The immunopathology of keratoconus: tear film biomarkers and immune pathways [0.03%]
角膜扩张的免疫病理学：泪液生物标志物和免疫途径
Marco Lombardo,Mario Fruschelli,Sebastiano Serrao
Marco Lombardo
Purpose of review: This review explores established risk factors for keratoconus and current insights into tear film immune biomarkers, with a focus on the role of chronic low-grade inflammation in disease pathogenesis an...
Alessandro Barone,Francesca Nicoletta,Martina Ottoni et al.
Alessandro Barone et al.
Purpose of review: Anaphylaxis in elderly is a little-known topic, despite the worldwide growth of this part of the population. In this review, the main elicitors are discussed, with a particular regard for risk factors, ...
Xin-Rong Lim,Bernard Yu-Hor Thong
Xin-Rong Lim
Purpose of review: Among the various manifestations of perioperative hypersensitivity (POH), skin reactions are often the first and most visible signs of an allergic or hypersensitivity response to drugs, antiseptics, or ...
Jessy Elst,Didier G Ebo,Vito Sabato
Jessy Elst
Purpose of review: Mast cell degranulation in anaphylaxis can result from both IgE-dependent and IgE-independent mechanisms. The two conditions differ in terms of phenotype, diagnosis and specific therapeutic targets. ...