Drug allergy in primary care: systematic review to support quality improvement initiative of management and optimization of healthcare pathways [0.03%]
初级保健中的药物过敏：系统评价助力医疗质量和路径优化提升行动
Clara Gaudin,Dermot Ryan,Pascal Demoly et al.
Clara Gaudin et al.
Purpose of review: The aim of this study was to review the practice of general practitioners (GPs) in regard to the diagnosis and management of drug hypersensitivity reactions (DHRs) to identify major challenges and to fa...
Highlights of the treatment of allergic rhinitis according to Chinese guidelines [0.03%]
中国指南关于过敏性鼻炎诊治要点分析
Min Zhang,Tian Ao,Lei Cheng
Min Zhang
Purpose of review: This review aimed to introduce the pharmacotherapy of allergic rhinitis according to the 2022 updated Chinese guidelines. Recent findin...
Serum tryptase and drug hypersensitivity: why, how and what? A systematic review [0.03%]
血清中溶酶和药物超敏反应：为什么、如何及现状？系统综述
Caroline Klingebiel,Wahib Belhocine,Joana Vitte
Caroline Klingebiel
Purpose of review: Serum tryptase, a mast cell marker, provides clues for the mechanism, severity, and management of drug hypersensitivity induced by immunoglobulin E dependent or independent mast cell activation. ...
Andrzej Bożek
Andrzej Bożek
Purpose of review: This review aims to present the current knowledge on the effectiveness and safety of allergen immunotherapy (AIT) in patients over 60 years of age with inhalant allergies. ...
Rocío Sáenz de Santa María,Marina Labella,Gádor Bogas et al.
Rocío Sáenz de Santa María et al.
Purpose of review: The use of contrast media is increasing in recent decades. Although gadolinium-based contrast agents (GBCAs) are generally well tolerated, adverse reactions, including hypersensitivity reactions (HSRs),...
Riccardo Castagnoli,Ilaria Brambilla,Mattia Giovannini et al.
Riccardo Castagnoli et al.
Purpose of review: This review aims to summarize the most recent advances in asthma management, focusing on novel approaches to pediatric asthma. Recent f...
Sebastian Ferri,Giovanni Paoletti,Corrado Pelaia et al.
Sebastian Ferri et al.
Purpose of review: Chronic Obstructive Pulmonary Disease (COPD) is a common, heterogeneous disease associated with abnormal inflammatory response of the lung to noxious particles and gases. The progression of disease lead...
New insights into the diagnosis and management of Stevens-Johnson syndrome and toxic epidermal necrolysis [0.03%]
对史蒂文斯-约翰逊综合征和中毒性表皮坏死溶解症诊断与治疗的新认识
Yuki Saito,Riichiro Abe
Yuki Saito
Purpose of review: Recent studies have been clarifying the pathogenesis and early diagnostic markers of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Additionally, the efficacy of tumor necrosis fac...
Diagnostic criteria of chronic conjunctivitis: atopic keratoconjunctivitis and vernal keratoconjunctivitis [0.03%]
过敏性结膜炎和春季角结膜炎的诊断标准及慢性结膜炎的诊断标准制定
Andrea Leonardi,Giuseppe Righetti,Giulia Giovannini et al.
Andrea Leonardi et al.
Purpose of review: Chronic ocular allergies, vernal (VKC) and atopic keratoconjunctivitis (AKC) are relatively rare conditions that require definite diagnostic criteria to the most appropriate therapeutical approach. ...
Transgenic murine models for the study of drug hypersensitivity reactions linked to HLA-I molecules [0.03%]
与HLA-I分子相关的药物超敏反应研究的转基因小鼠模型
Montserrat Puig,Michael A Norcross
Montserrat Puig
Purpose of review: Immune-mediated drug hypersensitivity reactions (DHRs) can be life-threatening and an impediment to drug development. Mechanism of disease studies are difficult to perform in humans. Here we review huma...