Laura Sams,Sonali Wijetilleka,Mark Ponsford et al.
Laura Sams et al.
Purpose of review: Allergy and atopic features are now well recognized manifestations of many inborn errors of immunity (IEI), and indeed may be the hallmark in some, such as DOCK8 deficiency. In this review, we describe ...
Shi-Ran Sun,Yin Yao,Zheng Liu
Shi-Ran Sun
Purpose of review: Emerging evidence indicating that the dysfunction of T follicular regulatory (T FR ) cells contributes to excessive immunoglobulin E (IgE) production and the development of allergic diseases. Conversely...
Neurotrophic keratitis: inflammatory pathogenesis and novel therapies [0.03%]
神经营养性角膜炎：炎症发病机制及新型治疗方法
Denise Wajnsztajn,Lana A Faraj,Sara Sanchez-Tabernero et al.
Denise Wajnsztajn et al.
Purpose of review: Neurotrophic keratitis is a rare degenerative disease characterized by decrease or absence of corneal sensation. Neurotrophic keratitis varies from mild forms with mild epitheliopathy to severe manifest...
Eden David,Tali Czarnowicki
Eden David
Purpose of review: As we continue to unravel the pathophysiology and immune mechanisms underlying atopic dermatitis (AD), the emergence of targeted treatments has provided new options for management. Although there are av...
Gianenrico Senna,Bianca Olivieri,Mariana Castells
Gianenrico Senna
Fabiana Furci,Nicoletta Luxi,Gianenrico Senna et al.
Fabiana Furci et al.
Purpose of review: To provide a better understanding of the risk of anaphylaxis due to antiallergic and antiasthmatic biologics through an analysis of data reported in literature and in clinical trials, and by conducting ...
Luciana Kase Tanno,Marco Caminati,Guillaume Pouessel et al.
Luciana Kase Tanno et al.
Purpose of review: To understand the current global scale of anaphylaxis and identify possible strategies to increase the accuracy of epidemiological data. ...
Barbara C Yang
Barbara C Yang
Purpose of review: The purpose of this literature review was to review the latest use of biologics in the management of anaphylaxis. The methodology was to highlight both the nonbiologic management of anaphylaxis and the ...
Atopic dermatitis and ocular allergy: common mechanisms and uncommon questions [0.03%]
特应性皮炎和眼部过敏：共同的机制与罕见的问题
Debajyoti Ghosh,Tesfaye B Mersha
Debajyoti Ghosh
Purpose of review: Atopic dermatitis (AD) and ocular allergy aka allergic eye disease (AED) are two common conditions that often coexist in patients. However, molecular connections between these two conditions are incompl...
Edward Fernandez,Elizabeth Phillips,Hajirah N Saeed
Edward Fernandez
Purpose of review: Many systemic medications have been observed to cause ocular toxicity. A subset of these reactions is thought to involve immunomodulation or a hypersensitivity reaction. As new medications are developed...