Junqin Bai,Bruce K Tan,Atsushi Kato
Junqin Bai
Purpose of review: This review aims to provide updates in realms of endotypic heterogeneity, pathogenesis at the molecular level, potential of biomarkers, and cutting-edge scope of biologics in CRS. ...
Interaction of eosinophilic and neutrophilic inflammation in patients with chronic rhinosinusitis [0.03%]
慢性鼻窦炎患者嗜酸性粒细胞和中性粒细胞炎症的相互作用
Yutong Sima,Xiangdong Wang,Luo Zhang
Yutong Sima
Purpose of review: In the past year, the endotype of chronic rhinosinusitis (CRS) has been studied from a new perspective. Eosinophilic and neutrophilic inflammation are not independent processes in the pathogenesis of CR...
SARS-CoV-2 vaccination in primary antibody deficiencies: an overview on efficacy, immunogenicity, durability of immune response and safety [0.03%]
原发性抗体缺陷患者接种萨斯冠状病毒-2疫苗的疗效、免疫原性、免疫反应持续时间及安全性概述
Gabriella Cusa,Germano Sardella,Giulia Garzi et al.
Gabriella Cusa et al.
Purpose of review: This review aims to summarize the current best knowledge on the efficacy of COVID-19 vaccination in vulnerable patients affected by primary antibody deficiencies (PADs), both in patients previously infe...
Laura De Ferrari,Anna Maria Riccio,Fulvio Braido
Laura De Ferrari
Purpose of review: Global Initiative for Asthma (GINA) document provides a classification of asthma severity according with the current level of treatment required to achieve diseases control and underlines the limitation...
Lisa M Ott de Bruin,Arjan C Lankester,Frank J T Staal
Lisa M Ott de Bruin
Purpose of review: Provide an overview of the landmark accomplishments and state of the art of gene therapy for inborn errors of immunity (IEI). Recent fi...
Kristin A Schmidlin,David I Bernstein
Kristin A Schmidlin
Purpose of review: The current review discusses allergen immunotherapy (AIT) safety in children. Recent findings: AIT is a well tolerat...
Neal P Sullivan,Nivethietha Maniam,Paul J Maglione
Neal P Sullivan
Purpose of review: Our goal is to review current understanding of interstitial lung disease (ILD) affecting patients with inborn errors of immunity (IEI). This includes understanding how IEI might predispose to and promot...
David Boutboul,Capucine Picard,Sylvain Latour
David Boutboul
Purpose of review: T-cell memory is a complex process not well understood involving specific steps, pathways and different T-cell subpopulations. Inborn errors of immunity (IEIs) represent unique models to decipher some o...
Susan Tadros,Siobhan O Burns
Susan Tadros
Purpose of review: This review outlines the principles of transition, summarizes current information about transition practices in inborn errors of immunity (IEI) and highlights general and specific considerations for tra...
Monogenic forms of common variable immunodeficiency and implications on target therapeutic approaches [0.03%]
单基因常见变量免疫缺陷的形式及对靶向治疗手段的启示
Giulio Tessarin,Manuela Baronio,Vassilios Lougaris
Giulio Tessarin
Purpose of review: Common variable immunodeficiency (CVID) is the most common symptomatic inborn error of immunity. The disorder is characterized by variable clinical and immunological manifestations, and, in a small mino...