The evolution of cyclosporine treatments for treatment of ocular surface diseases [0.03%]
环孢素治疗眼表面疾病的发展历程
Anna Flts,Richard Medina,Esen K Akpek
Anna Flts
Purpose of review: Cyclosporine is a versatile immunomodulatory drug commonly employed in modern medicine. Although cyclosporine was initially used to prevent solid organ transplant rejection, its indications have extende...
Novel therapeutic receptor agonists and antagonists in allergic conjunctivitis [0.03%]
过敏性结膜炎的新型治疗受体激动剂和拮抗剂
Sampson L Abu,Navpreet K Hehar,DeGaulle I Chigbu
Sampson L Abu
Purpose of review: Allergic conjunctivitis is characterized by the development of pathophysiological changes to the ocular surface, which occurs when pro-allergic and pro-inflammatory mediators interact with their cognate...
Evidence-based data support strategies for the prevention of Hymenoptera venom anaphylaxis [0.03%]
基于证据的数据支持防止膜翅目虫毒过敏策略
Audrey Kamga,Jean Luc Bourrain,Pascal Demoly et al.
Audrey Kamga et al.
Purpose of review: This review aims to identify phenotypes at-risk of Hymenoptera venom-induced anaphylaxis (HVA), focusing on different perspectives (epidemiological, clinical, and therapeutic) in order to adapt future p...
Riham Shawer,Abraham Solomon
Riham Shawer
Purpose of review: Cancer immunotherapy is one of the most emerging and rapidly growing fields.Ocular side effects associated with these therapies are common and can be present in up to 70% of patients.The cornea may be i...
Giovanni Paoletti,Federica Buta,Danilo Di Bona
Giovanni Paoletti
Lavinia Paternoster
Lavinia Paternoster
Purpose of review: This review summarizes recent advances in identifying genetic risk factors for atopic dermatitis and how these genetic associations are being used to explore the causal relationships between atopic derm...
Yashdeep Singh Pathania
Yashdeep Singh Pathania
Purpose of review: Chronic spontaneous urticaria (CSU) patients sometimes do not respond to second-generation antihistamine, and 10-50% patients do not even respond to four-fold the usual dose of nonsedating H1 antihistam...
Gwen S Stinnett,Chuan-Hui Kuo,Santa J Ono
Gwen S Stinnett
Purpose of review: The ocular surface is prone to inflammation due to exposure to environmental irritants and pathogens. Inflammasomes are intracellular, multiprotein complexes that communicate potentially dangerous signa...
Drug allergy awareness and perspectives with the implementation of the International Classification of Diseases-11 [0.03%]
国际疾病分类（第11版）实施背景下的药物过敏意识及展望
Luciana Kase Tanno,Yann Briand,Alain Perie et al.
Luciana Kase Tanno et al.
Purpose of review: To understand the current global scale of drug hypersensitivity (DH) and drug allergy (DA), and to identify possible strategies to increase the accuracy of epidemiological data. ...
Mast cell conditions and drug allergy: when to suspect and how to manage [0.03%]
mast细胞条件和药物过敏：何时怀疑及如何处理
Bianca Olivieri,Alessandro Ghilarducci,Francesca Nalin et al.
Bianca Olivieri et al.
Purpose of review: Patients with mast cell disorders frequently experience symptoms from excessive mediator release like histamine and tryptase, ranging from mild flushing to severe anaphylactic responses. Hypersensitivit...