Serial feature positive and feature negative discrimination learning in a taste avoidance preparation: implications for interoceptive control of behavior [0.03%]
序惯性特征正向和负向辨别学习在一种味觉回避准备中的作用:对内感受控制行为的启示
Shihui Huang,Sydney E Cerveny,Anna L Ruprecht et al.
Shihui Huang et al.
Background: Psychoactive drugs produce interoceptive stimuli that can guide appropriate behaviors by initiating or inhibiting responding. Objective: ...
Creatine supplementation protects spatial memory and long-term potentiation against chronic restraint stress [0.03%]
肌酸补充保护慢性束缚压力引起的时空记忆以及长期增益的丢失
Zahra Bahari,Zohreh Jangravi,Boshra Hatef et al.
Zahra Bahari et al.
Stress contributes to numerous psychopathologies, including memory impairment, and threatens one's well-being. It has been reported that creatine supplementation potentially influences cognitive processing. Hence, in this study, we examined...
Propranolol blocks the unconditioned and conditioned hyperactive effects of methamphetamine in CD-1 mice [0.03%]
普萘洛尔能阻断甲基苯丙胺在ICR小鼠身上的非条件和条件下的过度活化作用
Anthony S Rauhut
Anthony S Rauhut
The present experiment examined the contribution of the β-adrenergic receptor system in mediating the unconditioned (i.e. pharmacological) and conditioned (i.e. learned) hyperactive effects of methamphetamine. To this end, mice underwent a...
Liver tryptophan 2,3-dioxygenase: a determinant of anxiety-like behaviour - studies with chronic nicotine administration in rats [0.03%]
肝脏色氨酸2,3-双加氧酶:一种类似焦虑行为的决定因素-长期尼古丁给药实验中的研究结果
Samina Bano,Humaira Sharif,Faiza Sajid et al.
Samina Bano et al.
Deletion of the tryptophan 2,3-dioxygenase ( TDO2 ) gene induces an anxiolytic-like behaviour in mice and TDO inhibition by allopurinol elicits an antidepressant-like effect in rats exposed to restraint stress. Chronic nicotine administrati...
The mGlu2/3 agonist LY379268 reduces sucrose taking, seeking, and motivation in male and female rats [0.03%]
mGlu2/3激动剂LY379268可降低大鼠对蔗糖的摄入、寻取和动机反应
Jeffrey William Grimm,Frances Sauter,Derek MacDougall et al.
Jeffrey William Grimm et al.
Objectives: The mGlu2/3 receptor agonist LY379268 reduces sucrose-seeking, but not sucrose-taking, in male rats. This study explored the generality of this effect across the sexes. In addition, the effect of the drug on m...
Use of drug purchase tasks in medications development research: orexin system regulation of cocaine and drug demand [0.03%]
药物购买任务在药物开发研究中的应用:食欲素系统对可卡因和其他药物需求的调节作用研究
Justin C Strickland,Kevin W Hatton,Lon R Hays et al.
Justin C Strickland et al.
Commodity purchase tasks provide a useful method for evaluating behavioral economic demand in the human laboratory. Recent research has shown how responding to purchase tasks for blinded drug administration can be used to study abuse liabil...
Randomized Controlled Trial
Behavioural pharmacology. 2023 Aug 1;34(5):275-286. DOI:10.1097/FBP.0000000000000731 2023
Effect of l -Dopa in acute temozolomide-induced cognitive impairment in male mice: a possible antineuroinflammatory role [0.03%]
左旋多巴对雄性小鼠急性替莫唑胺致认知损伤的影响及潜在抗神经炎症作用的研究
Alireza Salarinejad,Khadije Esmaeilpour,Mohammad Shabani et al.
Alireza Salarinejad et al.
Temozolomide is used commonly in the treatment of some types of cancers, but it may also result in cognitive impairments such as memory deficits. l -Dopa, a well known medicine for the central nervous system, has been shown to have positive...
Agmatine prevents the memory impairment and the dysfunction of hippocampal GSK-3β and ERK signaling induced by aluminum nanoparticle in mice [0.03%]
腐植酸胺能防止铝纳米颗粒诱导的小鼠海马GSK-3β和ERK信号通路功能障碍及记忆损伤
Sadegh Izadi,Amin Rezaei,Zahra Esmaili et al.
Sadegh Izadi et al.
The growing usage of aluminum nanoparticles (Al-NP) and their exposure may influence body function. Considering the proposed relationship between Al and the pathogenesis of Alzheimer's disease and the concern about the effect of this nanopa...
The role of lateral habenula NMDA receptors in tramadol-induced conditioning [0.03%]
氯胺酮诱导条件作用的侧缰核NMDARs的作用
Arman Hajikarim-Hamedani,Amirhossein Heidari,Mitra-Sadat Sadat-Shirazi et al.
Arman Hajikarim-Hamedani et al.
The role of the lateral habenula (LHb) as a hub for receiving and relaying signals from the limbic system to serotonergic, dopaminergic, and norepinephrinergic regions in the brainstem makes this area a critical region in the control of rew...
Menstrual cycle influences on cue-induced smoking cravings and heart rate variability [0.03%]
月经周期对线索诱导的吸烟渴求和心率变异性的影响
Ashley Ethier,Laurie Sykes Tottenham,Jyotpal Singh et al.
Ashley Ethier et al.
Women experience greater difficulties in quitting smoking than men, though the hormonal factors contributing to this sex difference remain to be clarified. The current study aimed to examine menstrual cycle effects on smoking cue-induced cr...