Contextual and behavioral control of antipsychotic sensitization induced by haloperidol and olanzapine [0.03%]
卤operidol和奥氮平诱导的抗精神病药物敏感化的上下文和行为控制
Chen Zhang,Ming Li
Chen Zhang
Repeated administration of haloperidol (HAL) and olanzapine (OLZ) causes a progressively enhanced disruption of the conditioned avoidance response (CAR) and a progressively enhanced inhibition of phencyclidine (PCP)-induced hyperlocomotion ...
Maternal ethanol consumption by pregnant guinea pigs causes neurobehavioral deficits and increases ethanol preference in offspring [0.03%]
怀孕母 Guinea Pig 的乙醇摄取导致子代神经行为缺损并增加其对乙醇的偏好
Kayla M Shea,Amy J Hewitt,Mary C Olmstead et al.
Kayla M Shea et al.
The objective of this study was to test the hypothesis that prenatal exposure to ethanol, through maternal consumption of an aqueous ethanol solution, induces neurobehavioral deficits and increases ethanol preference in offspring. Pregnant ...
Repeated resveratrol administration confers lasting protection against neuronal damage but induces dose-related alterations of behavioral impairments after global ischemia [0.03%]
反复给予白藜芦醇可长时间保护全脑缺血后的神经元但会引起剂量相关的的行为损伤变化
Catrinel Girbovan,Lucie Morin,Hélène Plamondon
Catrinel Girbovan
Resveratrol, a naturally occurring polyphenol, has been shown to protect the heart and brain against ischemic injury. The current study investigated the effects of administration with either a 1 or 10-mg/kg dose of resveratrol on CA1 neuron...
Diphenyl diselenide ameliorates cognitive deficits induced by a model of menopause in rats [0.03%]
二苯基二硒化物改善绝经模型大鼠认知障碍的作用及机制研究
Juliana T da Rocha,Simone Pinton,Alexandre Mazzanti et al.
Juliana T da Rocha et al.
Ovarian hormone loss contributes to cognitive decline in postmenopausal women. Studies have demonstrated a positive role of the level of the element selenium in cognitive performance. The present study investigated the effects of the synthe...
Intrahippocampal injection of brain-derived neurotrophic factor increases anxiety-related, but not panic-related defensive responses: involvement of serotonin [0.03%]
脑源性神经营养因子海马内注射增加焦虑样但不增加惊恐样的防御反应：血清素参与作用
Plinio C Casarotto,Valquiria C de Bortoli,Hélio Zangrossi Jr
Plinio C Casarotto
Changes in brain-derived neurotrophic factor (BDNF)-mediated signaling in the hippocampus have been implicated in the etiology of depression and in the mode of action of antidepressant drugs. There is also evidence from animal studies to su...
Influence of sigma-1 receptor modulators on ethanol-induced conditioned place preference in the extinction-reinstatement model [0.03%]
σ-1受体调节剂对乙醇诱导的条件位置偏好在消退再燃模型中的影响
Pravinkumar S Bhutada,Yogita R Mundhada,Yogesh R Ghodki et al.
Pravinkumar S Bhutada et al.
Sigma-1 receptor agonists are reported to augment and antagonists block the rewarding effects of drugs of abuse. However, their effect on reinstatement of ethanol-induced conditioned place preference (CPP) has not yet been explored. Therefo...
Altered spatial learning and delay discounting in a rat model of human third trimester binge ethanol exposure [0.03%]
人晚期妊娠酗酒暴露大鼠模型的空间学习和延迟贴现的改变
Cristina Bañuelos,Ryan J Gilbert,Karienn S Montgomery et al.
Cristina Bañuelos et al.
Ethanol exposure during perinatal development can cause cognitive abnormalities including difficulties in learning, attention, and memory, as well as heightened impulsivity. The purpose of this study was to assess performance in spatial lea...
The peripheral L-arginine-nitric oxide-cyclic GMP pathway and ATP-sensitive K⁺ channels are involved in the antinociceptive effect of crotalphine on neuropathic pain in rats [0.03%]
矛头蝮蛇Crotoalphine在大鼠神经痛中的镇痛作用与外周L-精氨酸-一氧化氮-cGMP通路和ATP依赖的钾通道有关
Vanessa P Gutierrez,Vanessa O Zambelli,Gisele Picolo et al.
Vanessa P Gutierrez et al.
Crotalphine, a 14 amino acid peptide first isolated from the venom of the South American rattlesnake Crotalus durissus terrificus, induces a peripheral long-lasting and opioid receptor-mediated antinociceptive effect in a rat model of neuro...
Effects of developmental nicotine exposure in rats on decision-making in adulthood [0.03%]
大鼠发育期接触尼古丁对其成年后决策能力的影响
Marci R Mitchell,Ian A Mendez,Colin M Vokes et al.
Marci R Mitchell et al.
Exposure to tobacco smoke during pregnancy is associated with a range of adverse outcomes in offspring, including cognitive deficits and increased incidence of attention deficit-hyperactivity disorder, but there is a considerable controvers...
Learning impairment by Δ(9)-tetrahydrocannabinol in adolescence is attributable to deficits in chunking [0.03%]
大麻酚对青少年的不良影响是由于其在分块处理方面的缺陷所致
Ryan W J Steel,John H Miller,Dalice A Sim et al.
Ryan W J Steel et al.
Cannabis is the most popular illicit drug used by adolescents. Yet, there are only a few studies that have examined the effects of cannabis use on learning and memory during this sensitive and important neurodevelopmental stage. Male adoles...