Dynamic procalcitonin-guided antibiotic stewardship among cancer patients in the UK [0.03%]
动态引导英国防癌抗生素滥用行为的效果研究：促细胞因子淀粉样蛋白作为指导工具的疗效和安全性多中心随机临床试验
Dowan Kwon,Philip Williams,Helen Winter
Dowan Kwon
Introduction. Procalcitonin has been recognized as a tool for effective antibiotic stewardship to reduce unnecessary antibiotic use; however, its effectiveness remains unknown in the oncology setting, where infections are common and antibio...
Microbial profiling of five traditional Chinese medicines: culture-based identification vs. 16S rRNA sequencing [0.03%]
五种传统中药的微生物谱分析：基于培养鉴定与16S rRNA测序比对
Banzhan Ruan,Shi Li,Caixia Chen et al.
Banzhan Ruan et al.
Introduction. Traditional Chinese medicines (TCMs) may carry microbial hazards, yet conventional inspection methods often underestimate their diversity and risks.Hypothesis. Culture-based methods may overlook significant microbial diversity...
Comparative Study
Journal of medical microbiology. 2026 Mar;75(3):002137. DOI:10.1099/jmm.0.002137 2026
Eunice A Ayerakwa,Edward J A Douglas,Gerald Larrouy-Maumus et al.
Eunice A Ayerakwa et al.
Introduction. Antibiotic heteroresistance presents a growing public health concern, as the phenotype is associated with treatment failure and is hard to detect using conventional diagnostic testing.Gap Statement. Heteroresistance in Klebsie...
Waddlia chondrophila: from a bovine abortigenic agent to a potential cause of human adverse pregnancy outcomes [0.03%]
楔形体肺炎支原体：从一种牛流产病原菌到一种人类不良妊娠结局的潜在致病因子
Carole Kebbi-Beghdadi,David Longbottom,Hanna Marti et al.
Carole Kebbi-Beghdadi et al.
Waddlia chondrophila is a strict intracellular bacterium belonging to the Chlamydiales order, which also encompasses important human and animal pathogens, including Chlamydia trachomatis and Chlamydia psittaci. Like all other members of the...
Differences in gut microbiota and faecal metabolomics characteristics in preterm infants with feeding intolerance [0.03%]
早产儿喂养不耐受的肠道菌群及粪便代谢物特征差异分析
Jinya Wang,Jiejing Zhang,Ji Wang et al.
Jinya Wang et al.
Introduction. Feeding intolerance (FI) is one of the most common clinical issues in preterm infants, and there are currently no internationally unified diagnostic criteria.Gap Statement. Screening valuable biomarkers and evaluating their di...
Evaluating the use of whole-genome sequencing and Sanger emm typing in guiding the identification and public health management of invasive group A Streptococcus clusters and outbreaks in England [0.03%]
全基因组测序和Sanger emm分型在指导英国侵袭性A群链球菌群集和暴发识别及公共卫生管理中的应用评价研究
Kathrin Loosli,Juliana Coelho,Kartyk Moganeradj et al.
Kathrin Loosli et al.
Introduction. Sanger sequencing-based emm typing has traditionally been used in England to assess case relatedness when managing invasive group A Streptococcus (iGAS) outbreaks.Gap statement. While timely, emm typing can lack resolution. Wh...
Anaerobic microbiota promote pathogen association with the airway epithelium [0.03%]
缺氧菌群促进病原体与气道上皮的结合
Patrick J Moore,Leslie A Kent,Ryan C Hunter
Patrick J Moore
Introduction. Chronic rhinosinusitis (CRS) is a prevalent condition characterized by mucus stasis, persistent inflammation and infection of the paranasal sinuses. CRS often involves infection by the bacterium Pseudomonas aeruginosa, especia...
Understanding Candidozyma (Candida) auris: genomic evolution, antifungal resistance and the growing challenges in global infection control [0.03%]
解读白色念珠菌（耳念珠菌）auris：基因组进化、抗真菌耐药性和全球感染控制面临的挑战
Karoline Kristina Kemmerich,Suélen Andreia Rossi,João Nóbrega de Almeida Júnior et al.
Karoline Kristina Kemmerich et al.
Candida auris (recently renamed Candidozyma auris) is an emerging multidrug-resistant fungal pathogen, first identified in Japan in 2009. C. auris exhibits remarkable persistence on human skin and inanimate surfaces, resistance to multiple ...
Assessment of SARS-CoV-2 genome sequence recovery from four lateral flow device products available in the UK [0.03%]
四种英国市场上的侧向流动设备产品回收SARS-CoV-2基因组序列的评估研究
Kuiama Lewandowski,Matthew Stokes,Alexandra Alexandridou et al.
Kuiama Lewandowski et al.
Introduction. Lateral flow tests have played a key role in the response to the COVID-19 pandemic and are likely to be a major component of diagnostic strategies to combat future outbreaks of infectious disease.Gap Statement. One challenge p...
Functional and molecular characterization of Aspergillus fumigatus phosphoglucomutase (Pgm): a potential target for antifungal therapy [0.03%]
烟曲霉糖磷酸变位酶(Pgm)的功能和分子表征及其作为抗真菌治疗靶点的潜力
Conrad C Achilonu,Theodore J Kottom,Andrew H Limper
Conrad C Achilonu
Introduction. Aspergillus fumigatus phosphoglucomutase (AfPGM) is a central enzyme in fungal carbohydrate metabolism that catalyses the interconversion of glucose-1-phosphate and glucose-6-phosphate, generating precursors such as uridine di...