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Evaluating the use of whole-genome sequencing and Sanger emm typing in guiding the identification and public health management of invasive group A Streptococcus clusters and outbreaks in England

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Introduction. Sanger sequencing-based emm typing has traditionally been used in England to assess case relatedness when managing invasive group A Streptococcus (iGAS) outbreaks.Gap statement. While timely, emm typing can lack resolution. Whole-genome sequencin... ...