Neuroprotective effects of an oxindole-piperine hybrid in a rat model of ischemic stroke [0.03%]
一种氧化吲哚-胡椒碱衍生物对缺血性卒中大鼠的神经保护作用
Al-Shaimaa F Ahmed,Taha F S Ali,Momen R Fareed et al.
Al-Shaimaa F Ahmed et al.
Objective: Numerous studies suggest that oxindole-based derivatives exert neuroprotective activity on neurons. However, these studies used in-vitro evaluation methods and were not evaluated in vivo. Thus, this study aimed...
Multiscale neurobiological architecture of functional synchronization abnormalities in primary angle-closure glaucoma: an imaging-transcriptomics study [0.03%]
原发性闭角型青光眼功能同步异常的多尺度神经生物学结构：一项影像遗传学研究
Xian-Sheng Liu,Zi-Liang Zheng,Cao Jie
Xian-Sheng Liu
Background: Primary angle-closure glaucoma (PACG) induces widespread central nervous system remodeling. However, the molecular, cellular, and neurochemical architectures driving macroscopic functional synchronization abno...
Multimodal analysis of resting-state functional MRI in acute mild traumatic brain injury patients and its association with clinical cognitive performance [0.03%]
急性轻度创伤性脑损伤患者静息态功能磁共振的多模态研究及其与临床认知表现的关系
Peng Li,Ming Chen,Tiechen Xiao et al.
Peng Li et al.
Objective: Resting-state functional MRI (rs-fMRI) was used to measure the differences in voxel-based indicators between patients with acute mild traumatic brain injury (mTBI) and healthy volunteers, and the correlation be...
Frequency-dependent alterations of degree centrality in patients with poststroke depression: a resting-state functional MRI study [0.03%]
基于静息态功能磁共振成像的卒中抑郁患者频段依赖的功能连接及中枢改变研究
Shixin Wu,Sangsang Chen,Hao Chen et al.
Shixin Wu et al.
Background: Poststroke depression (PSD) severely impedes functional recovery among stroke survivors. However, the neural mechanisms underlying PSD remain poorly understood. This study aimed to investigate aberrant intrins...
Event-related potential evidence for memory prioritization modulated by social labels [0.03%]
社会标签对记忆优先级的影响的事件相关电位研究
Kimiko Kato,Kazuhito Yoshizaki
Kimiko Kato
Objective: We investigated whether semantic activation induced by social labels modulates memory prioritization during encoding, as indexed by event-related potentials (ERPs). Specifically, we examined semantic processing...
Continuous theta burst stimulation over the dorsolateral prefrontal cortex improves force steadiness during submaximal contractions without visual feedback [0.03%]
连续θ重复经颅磁刺激对背外侧前额叶皮质改善无视觉反馈下的次最大收缩力的稳定性
Taishi Okegawa,Naotsugu Kaneko,Daiki Yamasaki et al.
Taishi Okegawa et al.
Background: Without visual feedback, the central nervous system must rely on the integration of internal models and proprioceptive information. While the dorsolateral prefrontal cortex (DLPFC) is involved in motor control...
Multimodal characterization of cortical amplitude of low-frequency fluctuation alterations in chronic low back pain: integrating functional MRI, transcriptomics, and neurochemical mapping [0.03%]
慢性下背痛的皮层低频波动幅度多模态表征：整合功能磁共振成像、转录组学和神经化学映射
Yuan-Zhi He,Zhan-Xiang Hu,Xin Wan
Yuan-Zhi He
Background: Chronic low back pain (CLBP) is associated with widespread disruptions in intrinsic brain activity; however, the underlying molecular and neurochemical mechanisms remain unclear. This study aimed to elucidate ...
Electroacupuncture alleviates neuroinflammation and promotes recovery of neurological functions after intracerebral hemorrhage by modulating α7nAChR/JAK2/STAT3 signaling pathway [0.03%]
电针通过调节α7nAChR/JAK2/STAT3信号通路缓解脑出血后神经炎症及促进神经功能恢复
Hongling Xu,Yun Wang,Liu Zi et al.
Hongling Xu et al.
Objectives: Electroacupuncture, a therapeutic modality integrating electrical stimulation with traditional acupuncture, has emerged as a promising intervention for intracerebral hemorrhage (ICH). This study aimed to eluci...
Non-cell-autonomous regulation of Bhlhb5 expression in cortical projection neurons by GABAergic interneuron development and position [0.03%]
皮质投射神经元中Bhlhb5表达的非自主调控作用于GABA能中间神经元的发育和位置
Xiaolei Song,Fengzhu Zhang,Danyu Han et al.
Xiaolei Song et al.
Objective: The functional architecture of the cerebral cortex relies on the coordination between excitatory projection neurons and inhibitory GABAergic interneurons. While intrinsic programs governing their specification ...
C-C motif chemokine ligand 3 mediates inflammatory response via NLRP3 inflammasome and neuron damage after traumatic brain injury [0.03%]
C- motif 趋化因子配体3通过NLRP3炎性小体和神经元损伤在脑外伤后介导炎症反应
Shaozhuang Xue,Zhangyi Wang,Wu Ji et al.
Shaozhuang Xue et al.
Objective: Traumatic brain injury (TBI) constitutes a major inducer of neuroinflammation within the initial 24 h, peak microglial reactivity by day 3 post-injury, and cytokine production through day 7. However, the precis...