Ninety-six-week observational outcomes of long-acting injectable HIV therapy in people with adherence challenges, including people who use drugs [0.03%]
长效注射型人类免疫缺陷病毒疗法（用于治疗具有服药依从性问题的人群，包括药物使用者）96周观察结果
Lily Ostrer,Elizabeth Hastie,Laura Bamford et al.
Lily Ostrer et al.
Objective: To evaluate virological outcomes of people with HIV (PWH) and adherence challenges to oral antiretroviral therapy (ART) who initiate long-acting injectable ART. ...
Evolving drivers of preexposure prophylaxis discontinuation among US MSM, 2018-2024 [0.03%]
美国MSM人群在2018年至2024年间停止暴露前预防的因素演变
Samuel M Jenness,Bevin Manuelpillai,Steven M Goodreau et al.
Samuel M Jenness et al.
Objective: To examine temporal trends in reasons for stopping preexposure prophylaxis (PrEP) among MSM from 2018 to 2024, including how reasons co-occur and vary by demographics. ...
Distinct associations of peripheral mtDNA copy number and bioenergetic function with cognition in women with HIV and psychiatric comorbidities [0.03%]
HIV和精神共病女性中外周线粒体DNA拷贝数与生物能量功能的差异与认知之间的关联
Hannah Stadtler,Leah H Rubin,Gretchen N Neigh
Hannah Stadtler
Background: Women with HIV (WWH) are disproportionately affected by cognitive impairment across multiple domains, with learning and memory consistently among the most vulnerable. Mechanistic investigations into the increa...
Two-year efficacy and safety of long-acting cabotegravir and rilpivirine in the SCohoLART study [0.03%]
长效卡博特格拉韦和利匹韦林在SCohoLART研究中两年疗效及安全性分析
Camilla Muccini,Nicolò Capra,Riccardo Lolatto et al.
Camilla Muccini et al.
Background: Long-acting drugs were recently introduced for HIV treatment, so there are no medium-term or long-term data in real-world settings. Aims were to assess the cumulative probability of treatment discontinuation a...
Longitudinal patterns of kidney function in children with HIV: insights from group-based trajectory modeling [0.03%]
基于组的轨迹模型在HIV感染儿童中纵向探究肾功能模式
Soumya Tiwari,Viswas Chhapola,Srashti Garg et al.
Soumya Tiwari et al.
Objectives: Kidney dysfunction is increasingly recognized in children with HIV (CWH). We aimed to identify longitudinal patterns of kidney function in a hospital-based cohort. ...
Safety of semaglutide on depressive symptoms among people with HIV in routine clinical care [0.03%]
塞meglutide在常规临床护理中对HIV感染者抑郁症状的安全性研究
Lara Haidar,Stephanie A Ruderman,Christine Leong et al.
Lara Haidar et al.
Background: Semaglutide, widely used for diabetes and obesity, has raised concerns about neuropsychiatric risks, including depression and suicidality. Given the high burden of depression among people with HIV (PWH), we as...
Initiating semaglutide therapy reduces tobacco cigarette smoking intensity among people with HIV [0.03%]
利拉鲁肽治疗可以减少HIV患者的烟草摄入量
Stephanie A Ruderman,Heidi M Crane,Lara Haidar et al.
Stephanie A Ruderman et al.
Background: Smoking remains a major public health issue in people with HIV (PWH). Given the recent uptake of semaglutide for weight management and/or diabetes treatment in PWH and emerging evidence of antiaddictive proper...
Parallel declines in antiretroviral therapy adherence by dried blood spot and electronic monitoring in Cape Town, South Africa [0.03%]
南非开普敦地区干血点法和电子监测的抗逆转录病毒治疗依从性平行下降现象
Christopher M Ferraris,Paul A D&#x;Avanzo,Justin Knox et al.
Christopher M Ferraris et al.
Among 250 adults with HIV (median age 34 years, IQR 27-42; 78% women), tenofovir diphosphate (TFV-DP) concentrations in dried blood spots and electronic adherence declined over 12 months. Mean TFV-DP fell from 1219 to 939 fmol/punch in men ...
Early-treated children with perinatal HIV show elevated monocyte activation into late childhood [0.03%]
围产期感染HIV并接受早期治疗的儿童在晚年的单核细胞活化水平升高
Claire R Davies,Tariq R Webber,Sahera Dirajlal-Fargo et al.
Claire R Davies et al.
Early ART initiation in children with perinatal HIV (CHIV) greatly improves long-term outcomes. However, little is known of the long-term inflammatory profile. Our longitudinal study compared 26 inflammatory markers in early treated CHIV an...