Parallel declines in antiretroviral therapy adherence by dried blood spot and electronic monitoring in Cape Town, South Africa [0.03%]
南非开普敦地区干血点法和电子监测的抗逆转录病毒治疗依从性平行下降现象
Christopher M Ferraris,Paul A D&#x;Avanzo,Justin Knox et al.
Christopher M Ferraris et al.
Among 250 adults with HIV (median age 34 years, IQR 27-42; 78% women), tenofovir diphosphate (TFV-DP) concentrations in dried blood spots and electronic adherence declined over 12 months. Mean TFV-DP fell from 1219 to 939 fmol/punch in men ...
Early-treated children with perinatal HIV show elevated monocyte activation into late childhood [0.03%]
围产期感染HIV并接受早期治疗的儿童在晚年的单核细胞活化水平升高
Claire R Davies,Tariq R Webber,Sahera Dirajlal-Fargo et al.
Claire R Davies et al.
Early ART initiation in children with perinatal HIV (CHIV) greatly improves long-term outcomes. However, little is known of the long-term inflammatory profile. Our longitudinal study compared 26 inflammatory markers in early treated CHIV an...
Tolerability of lopinavir/ritonavir versus dolutegravir in ART regimens [0.03%]
利托纳韦/洛匹那韦与多替拉韦在抗逆转录病毒疗法中的耐受性研究
Subhash Hira,Jai P Narain,Shivangi Pawar
Subhash Hira
Under pressure: a call to increase access to spinal manometers as a critical component of the management of cryptococcal meningitis [0.03%]
压力下的呼吁：增加脊柱压计的获取渠道，以应对隐球菌性脑膜炎管理中的关键问题
Jonathan Falconer,Jack Adams,Sile Molloy et al.
Jonathan Falconer et al.
Maternal and pregnancy outcomes in women offered daily oral preexposure prophylaxis during pregnancy and postpartum [0.03%]
孕期和产后向孕妇提供每日口服暴露前预防的效果及妊娠结局
Benjamin H Chi,Deborah Kacanek,Emily Brown et al.
Benjamin H Chi et al.
Objective: To compare maternal safety and pregnancy outcomes among women who did and did not use daily oral emtricitabine-tenofovir disoproxil fumarate (FTC/TDF) for preexposure prophylaxis (PrEP) during pregnancy and pos...
Lizzie O&#x;Brien,Samuel Cross,Namwa Wongkalasin et al.
Lizzie O&#x;Brien et al.
Background: Despite substantial progress, global HIV incidence remains far above the UNAIDS 2030 target of 220 000 annual acquisitions. Pre-exposure prophylaxis (PrEP) is highly effective, including long-acting agents wit...
Next step after PrEP: HIV prevention pathways among former PrEP users disengaged from care [0.03%]
PrEP之后的下一步行动——脱离护理的前PrEP使用者的HIV预防途径
Inge J M Willemstein,Janneke C M Heijne,Kenneth Yap et al.
Inge J M Willemstein et al.
Objectives: To gain insight into HIV prevention pathways of individuals following pre-exposure prophylaxis (PrEP) care disengagement at the Center of Sexual Health in Amsterdam (CSHA), the Netherlands, to improve preventi...
Cabotegravir/rilpivirine in pregnancy: early insights from clinical practice [0.03%]
卡博特格拉韦/利匹韦林在妊娠中的应用：临床实践的初步见解
Michaeline McGuinty,Pierre Giguère,Jonathan B Angel
Michaeline McGuinty
Objective: To describe early experience with the use of cabotegravir/rilpivirine (CAB/RPV) in pregnancy and make recommendations based on these observations. ...
Tom Sumner,Rebecca A Clark,Tomos O Prys-Jones et al.
Tom Sumner et al.
Background: In 2024, tuberculosis (TB) caused 160 000 deaths in people with HIV (PWH). Several new TB vaccines are in development. The best way to use new vaccines to reduce the TB burden in PWH, and how this may vary by ...