Determinants of long-acting cabotegravir plus rilpivirine discontinuation in real-world HIV care: insights from the RELATIVITY cohort [0.03%]
长效卡博特格拉韦联合利匹韦林在真实世界HIV治疗中停药的原因：RELATIVITY队列研究的启示
Jesús Troya,María Luisa Montes,María José Galindo et al.
Jesús Troya et al.
Objectives: To evaluate real-world persistence with long-acting cabotegravir plus rilpivirine (LAI-CAB+RPV) in a nationwide cohort of virologically suppressed adults, describe the main clinical and structural reasons for ...
Comprehensive study of cerebrospinal fluid β2-microglobulin, a marker of central nervous system immune activation in individuals with HIV [0.03%]
HIV感染者中枢神经系统免疫激活标志物脑脊液β2微球蛋白的全面研究
Birgitta Anesten,Henrik Zetterberg,Staffan Nilsson et al.
Birgitta Anesten et al.
Objective: Cerebrospinal fluid (CSF) β2-microglobulin (β2M) has not been fully characterized in people with HIV (PWH) in different categories of disease. ...
Islatravir distribution in plasma, peripheral blood mononuclear cells, and mucosal tissues after monthly oral dosing [0.03%]
每月一次口服给药后，Islatravir在血浆、外周血单个核细胞和黏膜组织中的分布情况
Craig W Hendrix,Sharon L Hillier,Linda-Gail Bekker et al.
Craig W Hendrix et al.
Objective: Islatravir is a nucleoside reverse transcriptase translocation inhibitor (NRTTI) under development for HIV-1 treatment. We aimed to evaluate the pharmacokinetics (PK) of islatravir and its active form, islatrav...
Cardiometabolic impact of dolutegravir as second-line therapy: secondary analysis of a randomized controlled trial [0.03%]
多替拉韦作为二线疗法的心血管代谢影响：一项随机对照试验的二次分析
Phyo Pyae Nyein,Mark W Donoghoe,Nnakelu Eriobu et al.
Phyo Pyae Nyein et al.
Objectives: To examine changes in weight after initiating different dolutegravir-based second-line antiretroviral regimens and to measure the impact of observed weight change on blood pressure and serum lipids. ...
Longitudinal molecular network analysis in Guangxi: implications for HIV control [0.03%]
广西纵向分子网络分析对艾滋病防控的启示
Xianwu Pang,Kailing Tang,Qin He et al.
Xianwu Pang et al.
Objective: Guangxi faces a persistent HIV epidemic driven by heterosexual transmission and aging populations. This study uses molecular network to examine network topology and dynamics over time, providing insights for HI...
Clinical composition of HIV/AIDS-related deaths during the COVID-19 pandemic: a nationwide natural experiment (2017-2024) [0.03%]
新冠肺炎大流行期间与HIV/AIDS相关的死亡的临床构成：一项全国范围内的自然实验（2017-2024）
Yordanis Enriquez Canto
Yordanis Enriquez Canto
Objective: To assess whether the coronavirus disease 2019 (COVID-19) pandemic altered the clinical composition of HIV/AIDS-related deaths in Peru, distinguishing HIV/AIDS-only deaths from HIV/AIDS-COVID deaths and examini...
Targeted cuts to Ryan White programs could raise HIV incidence by 8-17% in 30 US states and the District of Columbia [0.03%]
靶向削减莱恩·怀特项目经费可能使美国30个州和华盛顿哥伦比亚特区的艾滋病发病率提高8%-17%
Andrew Zalesak,Melissa Schnure,Ryan Forster et al.
Andrew Zalesak et al.
Using an HIV transmission model in 30 states and Washington DC, we simulated ending Ryan White services from Parts C and D and the Ending the HIV Epidemic and Minority AIDS initiatives in February 2026. We projected 23 883 additional infect...
N-acetyl-aspartyl-glutamate connects neuroinflammatory signatures to attention and working memory in people with HIV [0.03%]
N-乙酰天冬氨酰谷氨酰胺连接HIV患者的神经炎症特征与注意力和操作记忆之间的关系
Leah H Rubin,Atiksh Chandra,Jesse Alt et al.
Leah H Rubin et al.
Despite viral suppression, many people with HIV (PWH) experience persistent cognitive difficulties. We previously demonstrated that cerebrospinal fluid (CSF) N-acetyl-aspartyl-glutamate (NAAG) was associated with spatial attention and worki...
HIV-1 subtype diversity trends in a Northern California cohort [0.03%]
Northern California HIV-1型别多样性的发展趋势（1996至2015年）
Kaiming Tao,Philip L Tzou,Malaya K Sahoo et al.
Kaiming Tao et al.
Between 2000 and 2019, the Stanford Healthcare Clinical Virology Laboratory performed HIV-1 resistance testing for 9199 individuals in Northern California. Nonsubtype B viruses were identified in 3.5%, most often CRF01_AE (1.0%), subtype C ...