Heart failure with preserved ejection fraction (HFpEF): diagnosis and management for the general physician [0.03%]
射血分数保留的心力衰竭（HFpEF）：普通医师的诊断与治疗指南
Rosita Zakeri,Adam A Nabeebaccus
Rosita Zakeri
Heart failure (HF) with preserved ejection fraction (HFpEF) is becoming the dominant HF phenotype in clinical practice, reflecting population aging and increasing cardiometabolic disease. Contemporary HFpEF is recognised as a complex, syste...
Trends and Widening Inequities in Cardiovascular-Kidney-Metabolic Involvement in Cardiovascular Mortality: A National Spatiotemporal Analysis, 2014-2023 [0.03%]
2014-2023年心血管死亡的心血管-肾脏-代谢参与的全国时空分析趋势和日益加剧的不平等
Kaide Xia,Bingpeng Gao,Junwen Wang
Kaide Xia
Background: Cardiovascular-kidney-metabolic (CKM) conditions increasingly contribute to cardiovascular disease (CVD) mortality, but temporal trends in social inequities and geographic priorities remain unclear. We quantif...
Educating current and future healthcare professionals on evidence-based sustainable medicine [0.03%]
对基于证据的可持续医学进行教育，造福现役和未来医疗工作者
Katharine Creamer,William K Gray,Simon Tso et al.
Katharine Creamer et al.
Increasing recognition of the need to deliver environmentally sustainable healthcare has led to much new research in this field. Many studies now estimate a 'carbon footprint' of an area of healthcare and often go on to highlight potential ...
UK Foundation Programme training needs a national minimum standard for advanced life support [0.03%]
英国基础项目培训需要国家最低 advanced life support 标准
Adam Baker,Michael Okorie
Adam Baker
Since 2021, Advanced Life Support (ALS) has no longer been a mandatory requirement of the UK Foundation Programme. Although the shift towards capability rather than certification was educationally defensible, in practice it has created mark...
Prognostic Value of Left Atrial Diameter in Chronic Kidney Disease: The KNOW-CKD Study [0.03%]
左肾衰直径的预后价值：KNOW-CKD研究
Sang Heon Suh,Hong Sang Choi,Chang Seong Kim et al.
Sang Heon Suh et al.
Introduction: Left atrial enlargement (LAE), a hallmark of heart failure with preserved ejection fraction (HFpEF), is prevalent in chronic kidney disease (CKD), but its prognostic value for cardio-renal outcomes remains u...
The impact of primary percutaneous coronary intervention timing on prognosis in STEMI patients [0.03%]
STEMI患者行急诊经皮冠状动脉介入治疗的时间对预后的影响
Lihui Zhou,Jin Si,Ming Yi et al.
Lihui Zhou et al.
Background: The benefit of primary percutaneous coronary intervention (PPCI) performed beyond 6hours after ST-segment elevation myocardial infarction (STEMI) symptom onset remains uncertain. ...
Hypertension: a common, yet poorly managed condition. What can we do better? [0.03%]
高血压：一种常见但管理不足的疾病。我们还能做得更好吗？
Abilash Sathyanarayanan,Indranil Dasgupta,Ponnusamy Saravanan
Abilash Sathyanarayanan
Frailty Phenotype, Genetic Risk, and Long-Term Incident Systemic Lupus Erythematosus Risk: Insights from the UK Biobank Study Integrated with Multi-Omics Analysis [0.03%]
脆弱表型、遗传风险与长期系统性红斑狼疮发病风险：来自英国生物样本库研究的整合多组学分析见解
Peizhi Deng,Siyu Yan,Jianyun Lu
Peizhi Deng
Background: Frailty, a marker of biological aging and reduced physiological reserve, is linked to many chronic conditions, yet its role in the development of systemic lupus erythematosus (SLE) remains unclear. ...
A FeAsibility items Checklist for assessing implementation characTeristics of patient reported Outcome measures in Research, Regulation and Routine clinical care (FACTOR3): development and evaluation [0.03%]
用于评估患者报告结果量表在研究、监管和常规临床护理中实施特征的可行性检查清单（FACTOR3）：开发与评价
Asad Bhatty,Chris Wilkinson,Visvesh Jeyalan et al.
Asad Bhatty et al.
Study objective: Patient reported outcome measures (PROMs) provide valuable data to inform regulatory decision making, health technology assessment and routine clinical care. We aimed to develop a feasibility item checkli...
Comparative prognostic performance of SOFA-1 and SOFA-2 in patients with sepsis at ICU admission [0.03%]
序贯器官功能衰竭评分(SOFA-1和SOFA-2)在重症监护病房收治的脓毒症患者中的预测效果比较
Lifang Lin,Zhifei Fu,Hongxia Sun et al.
Lifang Lin et al.
Study objective: SOFA-1 underpins Sepsis-3 definitions but may no longer optimally reflect contemporary ICU practice; SOFA-2 was recently developed from large multinational datasets, yet its prognostic performance in sept...