Real-world impact of disease on functioning and activity: what is missed when using general instruments to estimate quality-adjusted life years [0.03%]
疾病对功能和活动的实际影响：使用通用仪器估算质量调整生命年时会遗漏什么方面的内容
Tingjian Yan,Jesse D Ortendahl,Eunice Chang et al.
Tingjian Yan et al.
Objective: Economic evaluations conducted to inform healthcare resource allocation often rely on quality-adjusted life years (QALYs) to measure therapeutic benefit. However, QALYs, with underlying health utilities estimat...
Missing diagnoses of congenital cytomegalovirus infection in electronic health records for infants with laboratory-confirmed infection [0.03%]
电子健康记录中对实验室确认感染婴儿的先天性巨细胞病毒感染漏诊问题
Alexandra Campione,Tatiana M Lanzieri,Emily Ricotta et al.
Alexandra Campione et al.
Congenital cytomegalovirus (CMV) is a leading cause of non-genetic sensorineural hearing loss and neurodevelopmental disabilities among US children. Studies using administrative healthcare databases have identified infants with congenital C...
COMET - effectiveness and tolerability of methocarbamol versus oral opioid-analgesics as add-on measure in patients with non-specific low back pain refractory to recommended 1st line treatments. A retrospective analysis of depersonalized propensity score matched open-label real-world 4-week data from the German Pain e-Registry [0.03%]
COMET - 甲氧那明相对于口服阿片类镇痛药作为一线治疗非特异性下腰痛无效患者的辅助措施的有效性和耐受性。来自德国疼痛电子注册表的匿名倾向得分匹配开放标签真实世界4周数据的回顾性分析
Michael A Ueberall,Gerhard Mueller-Schwefe
Michael A Ueberall
Background: To compare the 4-week effectiveness and tolerability of an add-on treatment with oral high dose methocarbamol (MET) vs long-acting oral opioid analgesics (LAO) in patients with non-specific low back pain (nsLB...
Bethan I Jones,Andrew Freedman,Melissa J Thomas et al.
Bethan I Jones et al.
Objectives: This study aimed to characterize the risk of people living with HIV (PLHIV) in the UK progressing to pre-specified HIV-associated comorbidities, compared with matched, HIV-negative controls. ...
Direct cost and healthcare resource utilization of patients with migraine before treatment initiation with calcitonin gene-related peptide monoclonal antibodies by the number of prior preventive migraine medication classes [0.03%]
使用降钙素基因相关肽单克隆抗体治疗前，根据先前预防性偏头痛药物种类数量分析患者的直接医疗成本和医疗资源利用情况
Shonda A Foster,Margaret Hoyt,Wenyu Ye et al.
Shonda A Foster et al.
Objective: This study compared all-cause direct cost and healthcare resource utilization (HCRU) among preventive migraine medication (PMM)-naïve patients and patients with up to 3 PMM category switches before initiating ...
Plain language summaries of publications of company-sponsored medical research: what key questions do we need to address? [0.03%]
公司资助的医学研究出版物的白话摘要：我们需要解决哪些关键问题？
Dawn Lobban,Jason Gardner,Robert Matheis;ISMPP PLS Perspectives Working Group
Dawn Lobban
Objectives: We aimed to gather multi-stakeholder insights on key issues relating to plain language summaries (PLS) of company-sponsored medical research to inform future industry recognized guidelines. ...
Cerebral mucormycosis: intranasal route to deliver amphotericin B for effective management? [0.03%]
脑 mucormycosis：鼻内途径送抗真菌药 amphotericin B 以达到有效治疗？
Ruqaiyyah Siddiqui,Mohamed Yehia Abouleish,Mustafa Khamis et al.
Ruqaiyyah Siddiqui et al.
As cerebral mucormycosis is devastating in nature, here we discuss possible use of the intranasal route, in comparison to or in addition to intravenous administration, as a therapeutic approach to manage cases of mucormycosis with central n...
How do systemic sclerosis manifestations influence patients' lives? Results from a survey on patients and caregivers [0.03%]
系统性硬化症的表现如何影响患者的生活？来自患者和护理者的调查结果
Ilaria Galetti,Sara di Nunzio,Laura Brogelli et al.
Ilaria Galetti et al.
Objective: To investigate the patient- and caregiver-reported impact of systemic sclerosis (SSc) manifestations (hand/feet/joint involvement and pulmonary complications) on the diagnostic and therapeutic journey, working ...
Ilaria Galetti
Ilaria Galetti