Liquid biopsy-directed therapy in primary bone lymphoma: venetoclax-Pola-R-CHP and CAR-T achieve molecular remission: a case report [0.03%]
液体活检指导原发骨淋巴瘤治疗1例报告:Venetoclax-POLA-R-CHP和CAR-T诱导分子学缓解
Zhang Jing,Zhao Qian,Ma Yan et al.
Zhang Jing et al.
Introduction: Primary bone lymphoma (PBL) is a rare extranodal subtype of diffuse large B-cell lymphoma (DLBCL) that poses significant diagnostic challenges due to nonspecific clinical and radiological features. Molecular...
Implementation of blood-based colorectal cancer screening: real-world adherence and outcomes [0.03%]
基于血液的结直肠癌筛查实施:真实世界的依从性和结果
Candice Graham-Adderton,Carmen E Guerra,Quyen Ngo-Metzger et al.
Candice Graham-Adderton et al.
Objective: The overall CRC screening adherence rate remains suboptimal, with only 58% of screen-eligible individuals in the United States up to date with screening. This analysis reports on real-world adherence, test outc...
Healthcare utilization and costs following RSV and influenza vaccination in older adults in the United States [0.03%]
美国老年人接种呼吸道合胞病毒和流感疫苗后的医疗保健利用与花费
Andy Bowe,Chris Barger,Lauren Esterly et al.
Andy Bowe et al.
Objective: To compare healthcare utilization and costs in RSV- and influenza-vaccinated vs unvaccinated and influenza-only vaccinated older, US adults in 2023. ...
Treatment sequencing patterns and healthcare resource utilization in patients with Crohn's disease initiating biologics: a 3-year retrospective claims-based analysis [0.03%]
类克诱导的克罗恩病患者的治疗方案及医疗资源利用情况:一项为期三年的回顾性分析
Magdaliz Gorritz,Navneet Upadhyay,Rifat Tuly et al.
Magdaliz Gorritz et al.
Objective: This study aimed to provide a comprehensive analysis of long-term treatment patterns, biologic treatment sequencing, healthcare resource utilization (HCRU), and costs in biologic-naïve patients with CD. ...
Clinical characteristics of inadequate response to csDMARDs and bDMARDs in patients with rheumatoid arthritis: a cross-sectional, large cohort, real-world practice study [0.03%]
类风湿关节炎患者对csDMARDs和bDMARDs疗效不佳的临床特征:一项横断面、大样本的真实世界实践研究
Shihan Xu,Yanhong Wang,Jiuliang Zhao et al.
Shihan Xu et al.
Objective: This study aims to identify clinical characteristics of inadequate response (IR) to conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs) and biological disease-modifying antirheumatic drugs ...
Enhancing digital evolution in Indian clinical trials: bridging technological, participant, and regulatory gaps [0.03%]
印度临床试验的数字进化:弥合技术、参与者和监管差距
Murali Krishna Moka,Deepalaxmi Rathakrishnan,D K Sriram et al.
Murali Krishna Moka et al.
The rapid evolution of digital technologies has transformed clinical trials, offering improved efficiency and broader patient participation. However, in India, the transition to digital clinical trials presents multiple challenges, includin...
The effect of changing thrombolytic treatment for acute ischemic stroke on healthcare resource usage from the perspective of healthcare professionals: a pilot study [0.03%]
从医疗保健专业人员的角度看急性缺血性卒中溶栓治疗变化对卫生资源使用的影响:一项初步研究
Katie Hayes,George Thomas,Marilena Appierto et al.
Katie Hayes et al.
Objective: This study aimed to investigate the potential impact of replacing alteplase with a single-bolus fibrinolytic agent, such as tenecteplase, on patient care, secondary care management and resource utilization, fro...
Incremental healthcare resource utilization and costs among people living with HIV with and without chronic kidney disease in the United States [0.03%]
美国HIV感染者合并与不合并慢性肾脏病的医疗资源利用和成本增量分析
Sean P Fleming,Shweta Kamat,Girish Prajapati et al.
Sean P Fleming et al.
Objective: To assess incremental all-cause healthcare resource utilization (HCRU) and costs among people living with HIV (PLWH) with and without chronic kidney disease (CKD) in the United States. ...
Profiles and diagnostic patterns of colorectal cancers among 602 patients attending a tertiary care center in Saudi Arabia for suspected colic disease [0.03%]
沙特阿拉伯三级医疗中心602例疑似腹痛疾病患者的结直肠癌特征及诊断模式
Kamaleldin B Said,Khalid F Alshammari,Ruba M Elsaid Ahmed et al.
Kamaleldin B Said et al.
Objectives: Owing to the peaking rates and the multifaceted nature of colorectal-cancers (CRC), understanding regional-epidemiology and clinicopathological-characteristics is critical. However, for the severe paucity in h...
Completing the colorectal cancer screening process: impact of eliminating cost-sharing for follow-up colonoscopy [0.03%]
结肠镜筛查费用对结直肠癌筛查完成率的影响:基于消除后续结肠镜检查自付费用的分析
Mallik Greene,Quang A Le,A Burak Ozbay et al.
Mallik Greene et al.
Introduction: Colorectal cancer (CRC) screening is recommended for average-risk adults, yet completion of the screening process requires follow-up colonoscopy after a positive stool-based test (SBT). Until recently, patie...