Value-based procurement and tenders for medical devices with application to wound care: international perspectives and practical opportunities [0.03%]
基于价值的医疗器械采购和招标在伤口护理领域的国际视角与实践机会
Paayal Seechoonparsad,Chrystalbelle Rogers,Jacqueline Soong et al.
Paayal Seechoonparsad et al.
Background: Chronic wounds impose a substantial and growing burden on healthcare systems worldwide, consuming significant resources while often delivering suboptimal patient outcomes. In parallel, value-based procurement ...
Reduced plasma APJ levels and APLNR G212A polymorphism in Syrian patients with coronary artery disease [0.03%]
叙利亚冠心病患者血浆APJ水平下降及APLNR基因G212A多态性研究
Maisaa Hassan Abd-Alkareem,Hussam Eddin Mohammed Shibli,Faizeh Ali Alquobaili
Maisaa Hassan Abd-Alkareem
Background: Coronary artery disease (CAD) remains a leading global cause of mortality. The apelin/apelin receptor (APJ) system has emerged as a novel pathway implicated in cardiovascular regulation and disease progression...
Consensus-based recommendations on treatment dosage for biofeedback-assisted pelvic floor muscle training in women with stress urinary incontinence: a Delphi study [0.03%]
基于共识的生物反馈辅助盆底肌训练治疗剂量指导建议：德尔菲研究
Shirley Zhaoxue Liu,Stanley John Winser,Yingchun Zhang et al.
Shirley Zhaoxue Liu et al.
Background: Stress urinary incontinence (SUI) is a prevalent condition among women. Biofeedback (BF)-assisted pelvic floor muscle training (PFMT) is a widely used conservative treatment, but there is no consensus on the d...
Anemia visits and clinical patterns after identification of low hemoglobin at health checkups among women of reproductive age in Japan: a real-world claims and health checkup data study (AWARD study) [0.03%]
日本育龄妇女健康检查中低血红蛋白筛查后的贫血门诊就诊及临床特征：基于真实世界理赔数据和体检数据的AWARD研究
Motoko Fukui,Kaori Koga,Takeshi Yanagida et al.
Motoko Fukui et al.
Objective: This study aimed to determine the status of anemia visits (doctor visits made with patients' intent to response to identification of low hemoglobin [Hb] levels at health checkups) and characterize the diagnosis...
Could targeting the gut microbiome provide a novel treatment option for intermittent claudication [0.03%]
针对肠道菌群的靶向治疗能否成为间歇性跛行的新治疗选择？
Joong Min Park,Ian Beckman,Christopher L Delaney
Joong Min Park
Peripheral artery disease is a highly prevalent, age-related inflammatory condition. Many patients are asymptomatic, while others progress to chronic limb-threatening ischemia associated with high rates of morbidity and mortality. In betwee...
Plain language summary looking at the impact of increased patient out-of-pocket costs on stopping oral anticoagulant treatment among Medicare beneficiaries with atrial fibrillation treated with apixaban [0.03%]
简易概述：调査医疗保险受益人自付费用增加对其口服抗凝治疗的影响——接受阿哌沙班治疗的房颤患者为例
Dionne M Hines,Rupesh Subash,Dominick Latremouille-Vian et al.
Dionne M Hines et al.
Serum calcium and liver injury in people living with HIV: a longitudinal cohort study in Southeast China [0.03%]
中国东南部HIV阳性人群的血清钙和肝损伤：一项纵向队列研究
Fang Liu,Lan Yu,Jinchuan Shi et al.
Fang Liu et al.
Background: Liver disease remains a major cause of non-AIDS-related morbidity and mortality in people living with HIV (PLWH). Calcium homeostasis is involved in multiple hepatic processes, but the clinical relationship be...
Cardio-oncology disparities in breast cancer: mapping the social gradient of dual disease burden [0.03%]
乳腺癌的心脏肿瘤差异：绘制双重疾病负担的社会梯度地图
Omar Obeidat,Ali Obeidat,Qusai Alqudah et al.
Omar Obeidat et al.
Breast cancer and cardiovascular disease (CVD) increasingly coexist as a major source of morbidity and mortality among survivors. As cancer survival improves, cardiovascular complications have emerged as a leading determinant of long-term o...
Comparative economic analysis of B-cell maturation antigen-targeted bispecific antibodies in triple-class exposed relapsed/refractory multiple myeloma: linvoseltamab versus teclistamab and elranatamab [0.03%]
靶向B细胞成熟抗原的双特异性抗体在三线治疗复发/难治性多发性骨髓瘤中的经济比较分析：linvoseltamab与teclistamab和elranatamab
Andrew J Portuguese,Timothy J Inocencio,Peter Quon et al.
Andrew J Portuguese et al.
Objective: To evaluate the total cost of care, average monthly treatment cost, and cost per outcome of linvoseltamab versus teclistamab and elranatamab in triple-class-exposed relapsed/refractory multiple myeloma (RRMM) u...
Nitrous oxide abuse prevalence, mechanisms, treatments and prevention [0.03%]
氧化亚氮滥用的流行病学、机制、治疗和预防措施研究进展
C Michael White,Lyla R White
C Michael White
We describe major changes in the nitrous oxide market fueling recreational use with a focus on prevalence, desired effects, adverse events, treatments, and public health interventions. Nitrous oxide is currently sold with easy and discreet ...