Percutaneous electrocoagulation (PAPS-PEC) for incompetent perforator veins: a cost-effective technical innovation for venous ulcer healing [0.03%]
皮电凝术（PAPS-PEC）治疗非功能穿通静脉：一种有效的技术革新方法用于静脉性溃疡愈合
Lun Tian,Naiding Zhang,Yunxia Gong et al.
Lun Tian et al.
Introduction: Incompetent perforator veins (IPVs) are a critical driver of refractory venous leg ulcers (VLUs). Guideline-endorsed endovenous thermal ablation techniques face substantial implementation barriers due to hig...
Economic burden of treatment resistant depression in Korea: a 28-day health-state-specific cost analysis [0.03%]
韩国难治性抑郁的经济负担：基于健康状态的28天成本分析
HyunYung Lee,Hyunha Kang,Jong-Woo Paik et al.
HyunYung Lee et al.
Background: Treatment-resistant depression (TRD) imposes a substantial economic burden on South Korea, yet limited cost data exist for the TRD stage. This study estimated the 28-day societal costs of TRD across distinct h...
HIV resistance to integrase strand-transfer inhibitors: disproportionality analysis of individual case safety reports from the WHO global safety database (VigiBase) [0.03%]
整合酶链转移抑制剂治疗失败导致的艾滋病病毒耐药性：来源于WHO全球安全数据库（VigiBase）个例安全报告的不对称分析研究
Helena Sclauser Basílio,Adriano Max Moreira Reis,Letícia Penna Braga et al.
Helena Sclauser Basílio et al.
Objective: to investigate whether drug resistance is differentially reported for integrase strand-transfer inhibitors (INSTIs) in a global pharmacovigilance database. ...
Tislelizumab plus chemotherapy vs placebo plus chemotherapy as first-line treatment of advanced gastric or gastroesophageal junction adenocarcinoma: patient-reported outcomes in the Asian subgroup of the RATIONALE-305 study [0.03%]
替雷利珠单抗联合化疗对比安慰剂联合化疗用于晚期胃癌或食管胃结合部腺癌一线治疗的患者报告结局：RATIONALE 305研究的亚洲人群亚组分析
Ken Kato,Rui-Hua Xu,Do-Youn Oh et al.
Ken Kato et al.
Objective: This study examined the patient-reported outcomes (PROs) in the Asian subgroup of patients from the RATIONALE-305 (NCT03777657) trial. Methods:...
Benefits and safety of brexpiprazole in adolescents living with schizophrenia: a plain language summary [0.03%]
布 Rexiaprel 在治疗青少年精神分裂症患者方面的疗效及安全性：简易语言总结
Caroline Ward,Milica Pejović Milovančević,Nanco Hefting et al.
Caroline Ward et al.
Real-world comparison of androgen receptor pathway ınhibitors versus docetaxel as first-line treatment in metastatic hormone-sensitive prostate cancer [0.03%]
用于转移性激素敏感型前列腺癌一线治疗的新型雄激素受体通路抑制剂与多西他赛的现实世界对比研究
Zeliha Birsin,Vali Aliyev,Selin Cebeci et al.
Zeliha Birsin et al.
Background: Androgen receptor pathway inhibitors (ARPIs) and docetaxel are established first-line treatment options for metastatic hormone-sensitive prostate cancer (mHSPC); however, no randomized head-to-head trials have...
Skin as a mirror of endocrine diseases: emerging biomarkers and targeted therapies [0.03%]
皮肤：内分泌疾病的镜像：新兴生物标志物及靶向治疗
Jenyfer M Fuentes-Mendoza,Marcio J Concepción-Zavaleta,Jean Pierre Villanueva-De La Cruz et al.
Jenyfer M Fuentes-Mendoza et al.
The skin acts as a reflection of systemic endocrine activity, revealing the complex interaction among hormonal, metabolic and immune mechanisms. This narrative review synthesizes current evidence on the molecular and clinical connections be...
Pharmacologic profiles and selection of preoperative oral anxiolytics: a narrative review [0.03%]
术前口服镇静药的药理特征及用药选择：叙事性综述
Kwon Hui Seo,Shu Chung Choi,Ji Yung Lee et al.
Kwon Hui Seo et al.
Preoperative anxiety is common and has clinical consequences. Pharmacologic premedication remains widely used; however, its effectiveness varies, in part due to misalignment between drug timing and peak anxiety, as well as differences in pa...
Prevalence and determinants of inpatient hypoglycemia among hospitalized adults with diabetes: a cohort study [0.03%]
糖尿病住院成人低血糖的患病率及影响因素：队列研究
Andrew Gerald Hua Kiong Tan,Florence Hui Sieng Tan,Wai Yin Yong et al.
Andrew Gerald Hua Kiong Tan et al.
Objective: Inpatient hypoglycemia is a serious yet often under-recognized threat to the safety and well-being of hospitalized people with diabetes. Evidence on its prevalence and predictors in non-critical care settings r...
Quantifying US healthcare provider preferences for the treatment of post-transplant cytomegalovirus infection using a discrete choice experiment [0.03%]
Zoe Raglow,Dan Kaul,Ana María Rodriguez et al.
Zoe Raglow et al.
Background: Post-transplant cytomegalovirus (CMV) infection is associated with poor patient outcomes. Treatment decisions are complex, involving patient/transplant characteristics, risk factors, and trade-offs between tre...