Real world data of a German Parkinson's disease population: effectiveness and safety of safinamide in routine clinical practice [0.03%]
德国帕金森病患者的真实世界数据：萨芬氨脂在常规临床实践中的有效性和安全性
Wolfgang H Jost,Ivonne Gluth,Jennifer C Lück et al.
Wolfgang H Jost et al.
Background: Parkinson's Disease (PD) is a common progressive neurodegenerative disorder that leads to an imbalance of various neurotransmitters and affects cognitive, motor and non-motor function. Safinamide inhibits mono...
Semaglutide versus tirzepatide for people with type 2 diabetes: cost of glycemic control in Austria, the Netherlands, Lithuania, and the United Arab Emirates [0.03%]
在奥地利、荷兰、立陶宛和阿拉伯联合酋长国的2型糖尿病患者中，关于司美格鲁肽与替西帕肽血糖控制成本的研究
Signe Baattrup Reitzel,Mette Bøgelund,Amaury Basse et al.
Signe Baattrup Reitzel et al.
Objectives: The glucagon-like peptide-1 agonist semaglutide and the dual glucose-dependent insulinotropic polypeptide tirzepatide have proven to significantly reduce glucose levels in people with type 2 diabetes. However,...
Impact of a multifaceted intervention on non-guideline-recommended prescribing of acid suppressive medications for stress ulcer prophylaxis in critically ill patients [0.03%]
一项多方位介入对重症监护病房患者非共识推荐使用的抑制胃酸药物预防性治疗的影响
Furong Han,Chao Zhang,Tong Li et al.
Furong Han et al.
Objective: To promote an effective strategy to improve the non-guideline-recommended prescribing (NGRP) of acid suppressive medications for stress ulcer prophylaxis (SUP) in critically ill patients and to evaluate the imp...
Cancer incidence and mortality trends in Asia based on regions and human development index levels: an analyses from GLOBOCAN 2020 [0.03%]
基于GLOBOCAN 2020不同区域和人类发展指数水平的亚洲癌症发病率和死亡率趋势分析
Senthil Rajappa,Manmohan Singh,Roberto Uehara et al.
Senthil Rajappa et al.
Objective: As Asian countries transition socially and economically to higher Human Development Index (HDI) levels, cancer trends are expected to shift to those seen in the Western World. A strong correlation also exists b...
A systematic literature review of the economic and healthcare resource burden of cytomegalovirus [0.03%]
人巨细胞病毒的经济和医疗资源负担的系统文献回顾
John Diaz-Decaro,Evan Myers,Jacek Mucha et al.
John Diaz-Decaro et al.
Objective: Cytomegalovirus (CMV) can infect individuals at any age, including infants, who may contract it from infected mothers (congenital CMV [cCMV]). Whereas CMV infection is typically asymptomatic or causes mild illn...
Meta-analysis and GRADE assessment of randomized controlled trials on the efficacy and safety of bimekizumab in psoriatic arthritis patients [0.03%]
生物素克ズマブ治疗银屑病关节炎有效性和安全性的 meta 分析和 GRADE 评估
Abdelrahman Mohamed Mahmoud
Abdelrahman Mohamed Mahmoud
Objective: A persistent immune-mediated inflammatory disorder called psoriatic arthritis affects about 25% of persons with psoriasis. Bimekizumab, a humanized monoclonal IgG1 antibody, is a novel therapeutic approach that...
Patient-reported outcomes validated in phase 3 clinical trials: a targeted literature review [0.03%]
基于患者报告结局的III期临床试验系统性文献回顾
Antonia Morga,Silvia Dibenedetto,Rocco Adiutori et al.
Antonia Morga et al.
Background: Regulatory guidance advises validation of patient-reported outcome (PRO) instruments prior to use in pivotal clinical studies, which may then be used to generate critical patient-centered evidence and support ...
Weight gain after antiretroviral therapy initiation in people living with HIV in the United States: analyses of electronic medical records and prescription claims [0.03%]
美国HIV患者开始接受抗逆转录病毒治疗后的体重增加：电子病历和处方索赔分析
Xiaohui Zhao,Girish Prajapati,Jenny Tse et al.
Xiaohui Zhao et al.
Background: Treatment guidelines recommend integrase strand transfer inhibitor (INSTI)-based antiretroviral therapy (ART) regimens for treatment naïve people living with HIV (PLWH) in the United States (US). This retrosp...
Understanding information (in)equity: influencing factors and medical information's role in bridging the gap [0.03%]
理解（信息）不平衡：影响因素及医疗信息的作用
Patrick McCurry,Alicia Alexander Cadogan,Gudrun Hubinger et al.
Patrick McCurry et al.
Medical Information in the pharmaceutical industry involves the creation and dissemination of evidence-based scientific medical content in response to questions about medicines and therapy areas for patients and healthcare professionals. He...
Lipoprotein(a) and the risk of recurrent coronary heart disease: the Dubbo Study [0.03%]
载脂蛋白(a)与冠心病复发风险：杜博研究
Leon A Simons,Judith Simons
Leon A Simons
Objective: Elevated Lipoprotein(a) [Lp(a)] has not been firmly established as a risk factor for recurrent coronary heart disease (CHD). The present analysis explored this relationship in senior citizens. ...