Medical ethics in the pre-pandemic era: an analysis of peer-reviewed original research and network structures [0.03%]
新冠疫情大流行之前的医学伦理学：同行评议原始研究与网络结构分析
Dörthe Brüggmann,Doris Klingelhöfer
Dörthe Brüggmann
Objective: Medical Ethics integrates scientific approaches from ethics, philosophy, religious studies, history, and sociology into all relevant fields and subdisciplines of medicine, biomedicine, and healthcare. However, ...
KDM5D expression in lung carcinoma and its association with clinicopathologic parameters and survival [0.03%]
肺癌中KDM5D的表达及其与临床病理参数和生存率的关系
Omer Faruk Dilbaz,Ramazan Ucak,Suleyman Halil et al.
Omer Faruk Dilbaz et al.
Background: Globally, lung cancer is the most common malignancy among males, with higher incidence and mortality rates than in females. Sex chromosome analyses may provide insights into these disparities. KDM5D, located o...
Vitamin D and ER levels of expression and other clinicopathologic characteristics in breast cancers [0.03%]
维生素D和雌激素受体水平及其他临床病理特征在乳腺癌中的表现形式
Nicholas Lambert,Jonathan Hammond,Ioannis A Voutsadakis
Nicholas Lambert
Background: Vitamin D is a steroid hormone with many vital physiological functions. There is extensive research suggesting that vitamin D additionally acts as a protective factor against the development and progression of...
Effectiveness and safety of pharmacologic agents for postoperative delirium: a narrative review [0.03%]
药物治疗术后谵妄有效性和安全性的叙述性回顾
Seongeun Park,Sehyun Kwon,Jun Suh Lee
Seongeun Park
Postoperative delirium (POD) is a common and distressing neuropsychiatric complication following major surgery, linked to prolonged hospitalization, increased mortality, and long-term cognitive decline. Despite its widespread clinical use, ...
Real-world experience of semaglutide 2.4 mg in the US: a retrospective analysis of profiles, satisfaction, and treatment patterns in people with obesity and overweight [0.03%]
司美格鲁肽2.4毫克在美国真实世界中的经验：肥胖和超重人群档案、满意度和治疗模式的回顾性分析
Yiqiao Zhang,Zhenxiang Zhao,Victoria Higgins et al.
Yiqiao Zhang et al.
Objective: To characterize treatment experiences, compliance with dosing frequency, and adherence to treatment regimen, and to assess factors associated with adherence and compliance among patients with obesity or overwei...
Optimizing the delivery of care to patients with advanced epithelial ovarian cancer receiving first-line maintenance treatment with a poly(ADP-ribose) polymerase inhibitor [0.03%]
改善聚腺苷二磷酸核糖聚合酶抑制剂初治维持治疗的一线晚期卵巢上皮性癌患者的护理效果
Thomas C Krivak,Michael Fung-Kee-Fung,Jennifer E MacDonald et al.
Thomas C Krivak et al.
Background: Despite the demonstrated clinical benefits of poly(ADP-ribose) polymerase inhibitors (PARPis), up to 25% of newly diagnosed patients are nonadherent. To maximize clinical outcomes, there is a need to identify ...
Percutaneous left atrial appendage closure in non-valvular atrial fibrillation with concomitant heart failure: a systematic review and meta-analysis of periprocedural and long-term outcomes [0.03%]
非瓣膜性房颤合并心力衰竭患者左心耳封堵术的围手术期及长期疗效的系统评价和meta分析研究
Muhammad Yusuf,Clonia Milla,Liani Amelia Chandra et al.
Muhammad Yusuf et al.
Objective: Heart failure (HF) frequently coexists with non-valvular atrial fibrillation (NVAF) and may adversely affect outcomes after percutaneous left atrial appendage closure (LAAC). However, data on the safety and eff...
Evaluating time to treatment intensification among drug naïve type 2 diabetes patients: a comparison of initial combination therapy vs step-therapy approaches [0.03%]
新诊断的2型糖尿病患者初始联合用药与阶梯治疗至治疗强度增强的时间评估：一种对比研究方法
Zahra Majd,Sai S Cheruvu,Hua Chen et al.
Zahra Majd et al.
Objective: To evaluate the impact of the initial pharmacotherapy approach - initial combination therapy vs. traditional step-therapy - on time to treatment intensification (TI) among drug naïve type 2 diabetes (T2D) pati...
Post hoc analysis of SURMOUNT-J: tirzepatide versus placebo and predicted 10-year cardiovascular disease risk in Japanese adults with obesity disease [0.03%]
SURMOUNT-J的事后分析： tirzepatide与安慰剂对照及日本肥胖患者预测的10年心血管疾病风险
Koichi Node,Rachel L Batterham,Hong Liu-Seifert et al.
Koichi Node et al.
Objective: Obesity management is central to reducing cardiovascular disease (CVD) risk. In the phase 3 SURMOUNT-J trial, tirzepatide significantly reduced body weight and improved cardiometabolic parameters versus placebo...
Correlations of coronary lp-PLA2 and angiotensin II levels with the severity of coronary artery stenosis in elderly patients with coronary heart disease: a retrospective case-control study [0.03%]
冠状动脉粥样硬化心脏病老年患者冠脉lp-PLA2和血管紧张素Ⅱ水平与冠脉狭窄程度相关性的病例对照研究
Huaqing Yao,Weiyong Xu,Rongtai Luo et al.
Huaqing Yao et al.
Objective: This study focused on the correlations of lipoprotein-associated phospholipase A2 (Lp-PLA2) and angiotensin II (Ang II) levels with the severity of coronary artery stenosis (CAS) in elderly patients with suspec...