Correction: Pharmacogenomics cascade testing (PhaCT): a novel approacre econd screench for preemptive pharmacogenomics testing to optimize medication therapy [0.03%]
修正：药物基因组级联检测（PhaCT）：一种新颖的预先药物基因组检测二步筛查方法以优化药物治疗
Don Roosan,Angela Hwang,Moom R Roosan
Don Roosan
Published Erratum
The pharmacogenomics journal. 2021 Feb;21(1):106. DOI:10.1038/s41397-020-00183-8 2021
Pharmacogenetics in clinical practice: current level of knowledge among Flemish physicians and pharmacists [0.03%]
临床实践中药物基因组学知识：佛兰德地区医师和药师的了解程度
Ahmed Edris,Anna Vanoverschelde,Pranvera Bushaj et al.
Ahmed Edris et al.
Over the past decade, pharmacogenetics (PGx) became an essential tool for personalized medicine although its clinical implementation is still limited. We aimed to assess the current level of knowledge, applications, and expectations of Flem...
Pediatric pharmacogenomics: challenges and opportunities: on behalf of the Sanford Children's Genomic Medicine Consortium [0.03%]
儿科药物基因组学的挑战和机遇：沙福儿童基因组医学协会报告
David Gregornik,Daria Salyakina,Marilyn Brown et al.
David Gregornik et al.
The advent of digital, electronic, and molecular technologies has allowed the study of complete genomes. Integrating this information into drug development has opened the door for pharmacogenomic (PGx) interventions in direct patient care. ...
Pharmacogenomics cascade testing (PhaCT): a novel approach for preemptive pharmacogenomics testing to optimize medication therapy [0.03%]
药物基因组级联测试（PhaCT）：一种新的预防性药物基因组检测方法以优化药物治疗方案
Don Roosan,Angela Hwang,Moom R Roosan
Don Roosan
The implementation of pharmacogenomics (PGx) has come a long way since the dawn of utilizing pharmacogenomic data in clinical patient care. However, the potential benefits of sharing PGx results have yet to be explored. In this paper, we ex...
Influence of CYP3A polymorphisms on tacrolimus pharmacokinetics in kidney transplant recipients [0.03%]
CYP3A基因多态性对肾移植受者他克莫司药代动力学的影响
Ibtissem Hannachi,Zohra Chadli,Emna Kerkeni et al.
Ibtissem Hannachi et al.
Tacrolimus is characterized by a highly variable pharmacokinetics (PK) and a small therapeutic window. It is metabolized specifically by the CYP3A isoenzymes. This study aimed to determine, in kidney transplant patients, the influence of di...
Correction: Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritization [0.03%]
哮喘药物不良反应的药物基因关联：系统评价和研究优先级划分的纠正意见
Charlotte King,Amanda McKenna,Niloufar Farzan et al.
Charlotte King et al.
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Published Erratum
The pharmacogenomics journal. 2020 Oct;20(5):746. DOI:10.1038/s41397-020-0178-x 2020
Genetic variation of pharmacogenomic VIP variants in Zhuang nationality of southern China [0.03%]
中国南部壮族人群药理基因组学VIP变异的遗传变异分析
Yuanwei Liu,Haiyue Li,Keqing Cao et al.
Yuanwei Liu et al.
Drug gene polymorphisms are strongly associated with disease. Previous studies have shown that the frequency of drug genes varies in different populations. At present, there are no reports about the polymorphism of the drug genome in the Zh...
Group-based pharmacogenetic prediction: is it feasible and do current NHS England ethnic classifications provide appropriate data? [0.03%]
基于群体的药物基因预测：这在英国国家医疗服务体系（NHS）的种族分类下可行吗？当前的数据是否适当？
Catherine J E Ingram,Rosemary Ekong,Naser Ansari-Pour et al.
Catherine J E Ingram et al.
Inter-individual variation of drug metabolising enzymes (DMEs) leads to variable efficacy of many drugs and even adverse drug responses. Consequently, it would be desirable to test variants of many DMEs before drug treatment. Inter-ethnic d...
Gene variants and treatment outcomes in antineutrophil cytoplasmic antibody-associated vasculitis [0.03%]
抗中性粒细胞胞浆抗体相关性血管炎的基因变异和治疗效果
Arno C Hessels,Jan Stephan F Sanders,Abraham Rutgers et al.
Arno C Hessels et al.
The introduction of immunosuppressive therapy for ANCA-associated vasculitis (AAV) has greatly improved outcomes, though patients now accumulate damage from vasculitis activity and adverse effects of treatment. Prediction of treatment outco...
ERCC2 gene single-nucleotide polymorphism as a prognostic factor for locally advanced head and neck carcinomas after definitive cisplatin-based radiochemotherapy [0.03%]
依托泊苷敏感性的分子预测因素筛查项目(VPS)：基线特征和剂量减少的分析
Maja Guberina,Ali Sak,Christoph Pöttgen et al.
Maja Guberina et al.
Identifying patients with locally advanced head and neck carcinoma on high risk of recurrence after definitive concurrent radiochemotherapy is of key importance for the selection for consolidation therapy and for individualized treatment in...