Antigen density and applied force control enrichment of nanobody-expressing yeast cells in microfluidics [0.03%]
抗原密度和作用力控制纳米抗体表达酵母细胞在芯片上的富集
Merlin Sanicas,Rémy Torro,Laurent Limozin et al.
Merlin Sanicas et al.
In vitro display technologies such as yeast display have been instrumental in developing the selection of new antibodies, antibody fragments or nanobodies that bind to a specific target, with affinity towards the target being the main facto...
Integrating microfluidics and synthetic biology: advancements and diverse applications across organisms [0.03%]
微流控技术与合成生物学的融合：在不同生物体中的进展和多样化应用
Chiara Leal-Alves,Zhiyang Deng,Natalia Kermeci et al.
Chiara Leal-Alves et al.
Synthetic biology is the design and modification of biological systems for specific functions, integrating several disciplines like engineering, genetics, and computer science. The field of synthetic biology is to understand biological proc...
Microfluidic approach to correlate C. elegans neuronal functional aging and underlying changes of gene expression in mechanosensation [0.03%]
基于微流控技术研究秀丽隐杆线虫机械刺激感应通路的功能老化及其基因表达变化的关系
Jason Wan,Jimmy L Ding,Hang Lu
Jason Wan
The aging process has broad physiological impacts, including a significant decline in sensory function, which threatens both physical health and quality of life. One ideal model to study aging, neuronal function, and gene expression is the ...
Huihui Xu,Zhaoxun Wang,Wei Wei et al.
Huihui Xu et al.
Liposomes have garnered significant attention owing to their favorable characteristics as promising carriers. Microfluidic based hydrodynamic flow focusing, or micro-mixing approaches enable precise control of liposome size during their syn...
Revolutionizing sample preparation: a novel autonomous microfluidic platform for serial dilution [0.03%]
颠覆样品前处理：一种新型微流体系列稀释自主平台
Dries Vloemans,Alexander Pieters,Francesco Dal Dosso et al.
Dries Vloemans et al.
Dilution is a standard fluid operation widely employed in the sample preparation process of many bio(chemical) assays. It serves multiple essential functions such as sample mixing with certain reagents at specific dilution ratios, reducing ...
Bridging barriers: advances and challenges in modeling biological barriers and measuring barrier integrity in organ-on-chip systems [0.03%]
从芯片器官系统模型看生物屏障的建立、挑战及完整性测量方法的发展与挑战
Alisa Ugodnikov,Henrik Persson,Craig A Simmons
Alisa Ugodnikov
Biological barriers such as the blood-brain barrier, skin, and intestinal mucosal barrier play key roles in homeostasis, disease physiology, and drug delivery - as such, it is important to create representative in vitro models to improve un...
High-resolution low-cost LCD 3D printing for microfluidics and organ-on-a-chip devices [0.03%]
高分辨率低成本LCD 3D打印在微流控和器官芯片器件中的应用
Houda Shafique,Vahid Karamzadeh,Geunyong Kim et al.
Houda Shafique et al.
The fabrication of microfluidic devices has progressed from cleanroom manufacturing to replica molding in polymers, and more recently to direct manufacturing by subtractive (e.g., laser machining) and additive (e.g., 3D printing) techniques...
A microfluidic microalgae detection system for cellular physiological response based on an object detection algorithm [0.03%]
一种基于物体检测算法的微藻细胞生理响应的微流控检测系统
Shizheng Zhou,Tianhui Chen,Edgar S Fu et al.
Shizheng Zhou et al.
The composition of species and the physiological status of microalgal cells serve as significant indicators for monitoring marine environments. Symbiotic with corals, Symbiodiniaceae are more sensitive to the environmental response. However...
Advanced sequencing-based high-throughput and long-read single-cell transcriptome analysis [0.03%]
基于先进测序技术的高通量及长读长单细胞转录组分析
Shanqing Huang,Weixiong Shi,Shiyu Li et al.
Shanqing Huang et al.
Cells are the fundamental building blocks of living systems, exhibiting significant heterogeneity. The transcriptome connects the cellular genotype and phenotype, and profiling single-cell transcriptomes is critical for uncovering distinct ...
Microfluidic particle counter visualizing mucosal antibodies against SARS-CoV-2 in the upper respiratory tract for rapid evaluation of immune protection [0.03%]
可视化测定上呼吸道黏膜抗SARS-CoV-2抗体的微流控颗粒计数器，可快速评估免疫保护力
Jiaheng Li,Lok Ting Chu,Hogi Hartanto et al.
Jiaheng Li et al.
Mucosal antibodies in the upper respiratory tract are the earliest and most critical responders to prevent respiratory infections, providing an indication for the rapid evaluation of immune protection. Here, we report a microfluidic particl...