Toward microfluidic continuous-flow and intelligent downstream processing of biopharmaceuticals [0.03%]
朝向生物药的微流体连续流及智能下游加工技术
Vikas Sharma,Amirreza Mottafegh,Jeong-Un Joo et al.
Vikas Sharma et al.
Biopharmaceuticals have emerged as powerful therapeutic agents, revolutionizing the treatment landscape for various diseases, including cancer, infectious diseases, autoimmune and genetic disorders. These biotherapeutics pave the way for pr...
Analytical validation of the DropXpert S6 system for diagnosis of chronic myelocytic leukemia [0.03%]
DropXpert S6系统诊断慢性粒细胞白血病的分析验证
Wenjia Wei,Shujun Li,Ying Zhang et al.
Wenjia Wei et al.
Digital PCR is a powerful method for absolute nucleic acid quantification and is widely used in the absolute quantification of viral copy numbers, tumor marker detection, and prenatal diagnosis. However, for most of the existing droplet-bas...
Automated dynamic inlet microfluidics system: 3D printer adaptation for cost-effective, low volume, on-demand multi-analyte droplet generator [0.03%]
一种自动化动态进样微流控系统：适应于低成本、低体积、按需多分析物液滴发生器的3D打印
Abdul Basit Zia,Justin Farrell,Ian G Foulds
Abdul Basit Zia
The paper demonstrates an adaptation of a 3D printer (Prusa Mini+) with novel modules to develop a droplet generation system that generates combinatorial droplets from a standard 96 well plate. The calibration methodology developed would al...
Emulation and evaluation of tumor cell combined chemotherapy in isotropic/anisotropic collagen fiber microenvironments [0.03%]
各向同性/各向异性胶原纤维微环境中肿瘤细胞联合化疗的仿真与评估
Lianjie Zhou,Guoqiang Li,Jingru Yao et al.
Lianjie Zhou et al.
The rapid emergence of anisotropic collagen fibers in the tissue microenvironment is a critical transition point in late-stage breast cancer. Specifically, the fiber orientation facilitates the likelihood of high-speed tumor cell invasion a...
Millifluidic magnetophoresis-based chip for age-specific fractionation: evaluating the impact of age on metabolomics and gene expression in yeast [0.03%]
基于磁介电迁移的亚型微流控芯片及其在解析模式生物年龄差异代谢组和转录组方面的作用
L Wittmann,M Eigenfeld,K Büchner et al.
L Wittmann et al.
A novel millifluidic process introduces age-based fractionation of S. pastorianus var. carlsbergensis yeast culture through magnetophoresis. Saccharomyces yeast is a model organism for aging research used in various industries. Traditional ...
The egg-counter: a novel microfluidic platform for characterization of Caenorhabditis elegans egg-laying [0.03%]
一种表征秀丽隐杆线虫产卵的新型微流体平台：蛋计数器
Stephen A Banse,Cody M Jarrett,Kristin J Robinson et al.
Stephen A Banse et al.
Reproduction is a fundamental process that shapes the demography of every living organism yet is often difficult to assess with high precision in animals that produce large numbers of offspring. Here, we present a novel microfluidic researc...
Raúl Fernández-Mateo,Pablo García-Sánchez,Antonio Ramos et al.
Raúl Fernández-Mateo et al.
Concentration-polarization electroosmosis (CPEO) refers to steady-state electroosmotic flows around charged dielectric micro-particles induced by low-frequency AC electric fields. Recently, these flows were shown to cause repulsion of collo...
Microfluidic device for the high-throughput and selective encapsulation of single target cells [0.03%]
一种用于高效捕捉并包封目标细胞的微流控装置
Masahiko Nakamura,Masahiro Matsumoto,Tatsumi Ito et al.
Masahiko Nakamura et al.
Droplet-based microfluidic technologies for encapsulating single cells have rapidly evolved into powerful tools for single-cell analysis. In conventional passive single-cell encapsulation techniques, because cells arrive randomly at the dro...
OMEF biochip for evaluating red blood cell deformability using dielectrophoresis as a diagnostic tool for type 2 diabetes mellitus [0.03%]
基于介电泳的红细胞变形能力评估型OMEF生物芯片及其在2型糖尿病诊断中的应用研究
Dima Samer Ali,Samuel O Sofela,Muhammedin Deliorman et al.
Dima Samer Ali et al.
Type 2 diabetes mellitus (T2DM) is a prevalent and debilitating disease with numerous health risks, including cardiovascular diseases, kidney dysfunction, and nerve damage. One important aspect of T2DM is its association with the abnormal m...
On the compatibility of single-cell microcarriers (nanovials) with microfluidic impedance cytometry [0.03%]
单细胞微载体（纳米管）与微流控阻抗式细胞计数法的兼容性研究
Cristian Brandi,Adele De Ninno,Filippo Ruggiero et al.
Cristian Brandi et al.
We investigate for the first time the compatibility of nanovials with microfluidic impedance cytometry (MIC). Nanovials are suspendable crescent-shaped single-cell microcarriers that enable specific cell adhesion, the creation of compartmen...